Font Size

Cushing Syndrome (cont.)


The outlook is favorable if surgery is curative.

The rare adrenal carcinomas are associated with a 5-year survival rate of 30% or less.

Two catastrophic medical crises that occur in corticosteroid excess states are perforated viscera (such as the stomach, duodenum, small intestine) and opportunistic saprophytic or fungal infections.

Exposure to excess corticosteroid results in multiple medical problems, including high blood pressure, obesity, osteoporosis, fractures, impaired immune function, impaired wound healing, glucose intolerance, and psychosis.

Exogenous steroids suppress the hypothalamic-pituitary-adrenal axis, with full recovery taking as long as a year after stopping corticosteroid medication. Thus, persons who are on or who have taken steroids are at risk for developing an adrenal crisis (a life-threatening condition caused by insufficient corticosteroid).

Medically Reviewed by a Doctor on 11/30/2015
Medical Author:
Medical Editor:
Medical Editor:
Medical Editor:

Must Read Articles Related to Cushing Syndrome

Obesity More than two-thirds of Americans are overweight, including at least one in five children. Nearly one-third are obese. Obesity is on the rise in our society ...learn more >>

Patient Comments & Reviews

The eMedicineHealth doctors ask about Cushing Syndrome:

Cushing Syndrome - Experience

Please describe your experience with Cushing's syndrome.

Cushing Syndrome - Symptoms

What were the symptoms of your Cushing's syndrome?

Cushing Syndrome - Medical Treatment

What was the treatment for your medical treatment?

Read What Your Physician is Reading on Medscape

Cushing Syndrome »

Cushing syndrome is caused by prolonged exposure to elevated levels of either endogenous glucocorticoids or exogenous glucocorticoids.

Read More on Medscape Reference »

Medical Dictionary