Font Size

Dementia Medication Overview (cont.)

Other Therapeutic Interventions for Dementia

Data continue to emerge regarding other potential interventions that may treat dementia or decrease the risk of developing it. Observations of the following interventions are preliminary and are considered uncertain regarding their benefit in preventing or delaying disease progression.

  • Selegiline (Eldepryl): Some studies have reported that selegiline, a drug used in the treatment of Parkinson disease, may improve behavior, functional performance, and cognitive function. Mood enhancement may play a role in the apparent improvement in cognition.
  • Estrogens: In women, estrogens may enhance nerve cell function after menopause.
  • Antioxidants: High doses of vitamin E (1000 units twice daily) may be beneficial in delaying functional deterioration in vascular dementia. Such high doses of vitamin E can cause bleeding problems in some people. The addition of vitamin C may enhance the beneficial effects.
  • Anti-inflammatory agents: Nonsteroidal anti-inflammatory drugs (NSAIDs) include agents like ibuprofen (Motrin, Advil) and naproxen (Aleve). NSAIDs may decrease inflammatory changes that are common in Alzheimer disease, or they may inhibit platelets, thereby protecting blood flow in the brain.
  • Statins: The Canadian Study of Health and Aging noticed that people using statins (for example, atorvastatin [Lipitor], pravastatin [Pravachol], or simvastatin [Zocor]) to lower cholesterol showed lower odds of developing Alzheimer disease.

Medically reviewed by Joseph Carcione, DO; American board of Psychiatry and Neurology


"Treatment of dementia"

Medically Reviewed by a Doctor on 12/23/2015
Medical Author:
Medical Editor:
Medical Editor:
Medical Editor:

Must Read Articles Related to Dementia Medication Overview

Dementia Due to HIV Infection
Dementia Due to HIV Infection Decline in mental processes is a common complication of HIV infection (and many other conditions). Although the specific symptoms vary from person to pers...learn more >>

Read What Your Physician is Reading on Medscape

Dementia: Overview of Pharmacotherapy »

Perhaps the most important challenge in treating dementia is identifying cases (albeit uncommon) of reversible dementia such as chronic drug intoxication, vitamin deficiencies (B-12 and folate), subdural hematoma(s), major depression (causing forgetfulness), normal pressure hydrocephalus (NPH), and hypothyroidism.

Read More on Medscape Reference »

Medical Dictionary