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Medications and Drugs

Brand Names: Talacen

Generic Name: acetaminophen and pentazocine (Pronunciation: a SEET a MIN oh fen and pen TAZ oh seen)

What is acetaminophen and pentazocine (Talacen)?

Acetaminophen is a pain reliever and a fever reducer.

Pentazocine is an opioid pain medication. An opioid is sometimes called a narcotic.

The combination of acetaminophen and pentazocine is used to treat mild to moderate pain.

Acetaminophen and pentazocine may also be used for purposes not listed in this medication guide.

Acetaminophen-Pentazocine 650 mg-25 mg-WAT

oblong, turquoise, imprinted with 396 25 650, WATSON


oblong, blue, imprinted with T 37, Winthrop

What are the possible side effects of acetaminophen and pentazocine (Talacen)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using acetaminophen and pentazocine and call your doctor at once if you have a serious side effect such as:

  • fast heart rate;
  • weak or shallow breathing, slow heartbeat;
  • feeling like you might pass out;
  • confusion, hallucinations, unusual thoughts or behavior;
  • severe headache, ringing in your ears, anxiety, chest pain;
  • seizure (convulsions);
  • easy bruising or bleeding; or
  • nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • feeling dizzy or drowsy;
  • mild nausea, vomiting, upset stomach, constipation, diarrhea;
  • dry mouth; or
  • blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about acetaminophen and pentazocine (Talacen)?

Tell your doctor if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take acetaminophen.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

This medication may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it.

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how acetaminophen and pentazocine will affect you.

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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