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Medications and Drugs

Brand Names: Ofirmev

Generic Name: acetaminophen (injection) (Pronunciation: a SEET a MIN oh FEN)

What is acetaminophen injection (Ofirmev)?

Acetaminophen is a pain reliever and a fever reducer.

Acetaminophen injection is used to treat pain and to reduce fever. Acetaminophen injection is sometimes given with opioid (sometimes called narcotic) pain medication to treat moderate to severe pain.

Acetaminophen injection may also be used for purposes not listed in this medication guide.

What are the possible side effects of acetaminophen injection (Ofirmev)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking this medication and call your doctor at once if you have a serious side effect such as:

  • nausea, upper stomach pain, itching, loss of appetite;
  • dark urine, clay-colored stools;
  • jaundice (yellowing of the skin or eyes); or
  • chest pain, trouble breathing.

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about acetaminophen injection (Ofirmev)?

You should not use this medication if you are allergic to acetaminophen, or if you have severe liver disease.

Do not use more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death.

Before using acetaminophen injection, tell your doctor if you have a history of alcoholism or liver disease (especially cirrhosis), or if you drink more than 3 alcoholic beverages per day.

Avoid drinking alcohol. It may increase your risk of liver damage while using acetaminophen injection.

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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