Brand Names: Gilotrif
Generic Name: afatinib
- What is afatinib (Gilotrif)?
- What are the possible side effects of afatinib (Gilotrif)?
- What is the most important information I should know about afatinib (Gilotrif)?
- What should I discuss with my healthcare provider before taking afatinib (Gilotrif)?
- How should I take afatinib (Gilotrif)?
- What happens if I miss a dose (Gilotrif)?
- What happens if I overdose (Gilotrif)?
- What should I avoid while taking afatinib (Gilotrif)?
- What other drugs will affect afatinib (Gilotrif)?
- Where can I get more information (Gilotrif)?
What is afatinib (Gilotrif)?
Afatinib is used to treat a certain type of non-small cell lung cancer that has spread to other parts of the body. Afatinib is used for this condition only if your tumor has a specific genetic marker for which your doctor will test.
Afatinib may also be used for purposes not listed in this medication guide.
What are the possible side effects of afatinib (Gilotrif)?
Stop using afatinib and call your doctor at once if you have:
- new or worsening cough, fever, or trouble breathing;
- severe or ongoing diarrhea (lasting 2 days or longer);
- severe skin reaction that causes blistering and peeling;
- pain, redness, numbness, and peeling skin on your hands or feet;
- blisters or ulcers in your mouth, red or swollen gums, trouble swallowing;
- eye problems--eye pain or redness, blurred vision, watery eyes, feeling like something is in your eye, increased sensitivity to light;
- liver problems--stomach pain (upper right side), easy bruising or bleeding, feeling tired, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
- heart problems--pounding heartbeats or fluttering in your chest, shortness of breath (even with mild exertion), swelling in your legs or ankles, rapid weight gain.
Common side effects may include:
- mild diarrhea for 1 day or less;
- nausea, vomiting, loss of appetite;
- mouth sores;
- acne, itching, dry skin; or
- redness, pain, swelling, or other signs of infection around your fingernails or toenails.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about afatinib (Gilotrif)?
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What should I discuss with my healthcare provider before taking afatinib (Gilotrif)?
You should not use afatinib if you are allergic to it.
Tell your doctor if you have ever had:
- kidney disease;
- liver disease;
- heart disease;
- breathing problems or lung disease other than cancer; or
- vision problems, very dry eyes, or if you wear contact lenses.
Afatinib may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 2 weeks after your last dose. Tell your doctor if you become pregnant.
Do not not breastfeed while using this medicine and for 2 weeks after your last dose.
How should I take afatinib (Gilotrif)?
Your doctor will perform a blood test to make sure afatinib is the right treatment for your condition.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take afatinib on an empty stomach, at least 1 hour before or 2 hours after a meal.
Your doctor may recommend you have an anti-diarrhea medicine such as loperamide (Imodium) available at all times while you are taking afatinib. Take the anti-diarrhea medicine as directed on the label, or as prescribed by your doctor.
Call your doctor if you are sick with severe diarrhea, or diarrhea lasting longer than 2 days. You may need to stop taking afatinib for a short time.
You will need frequent medical tests.
Store the tablets in their original container at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.
Throw away any afatinib tablets not used before the expiration date on the medicine label.
What happens if I miss a dose (Gilotrif)?
Use the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 12 hours. Do not use two doses at one time.
What happens if I overdose (Gilotrif)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking afatinib (Gilotrif)?
What other drugs will affect afatinib (Gilotrif)?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Other drugs may affect afatinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Where can I get more information (Gilotrif)?
Your pharmacist can provide more information about afatinib.
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