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Medications and Drugs

Brand Names: Kineret

Generic Name: anakinra (injectable) (Pronunciation: an na KIN rah)

What is anakinra (Kineret)?

Anakinra reduces the actions of chemicals in the body that are involved in inflammatory and immune responses.

Anakinra is used to treat the symptoms of moderate to severe rheumatoid arthritis in adults. Anakinra may also help slow the progress of the disease.

Anakinra is usually given after other arthritis medications have been tried without successful treatment of symptoms.

Anakinra may also be used for purposes not listed in this medication guide.

What are the possible side effects of anakinra (Kineret)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Serious infections may occur during treatment with anakinra. Stop using this medicine and call your doctor right away if you have signs of infection such as:

Less serious side effects may include:

  • nausea, diarrhea, stomach pain;
  • headache;
  • cold symptoms such as stuffy nose, sneezing, sore throat; or
  • redness, bruising, pain, or swelling where the injection was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about anakinra (Kineret)?

You should not use this medication if you are allergic to anakinra or to other medicines that contain E. coli bacteria proteins. You also should not use anakinra if you have an active infection.

Before using anakinra, tell your doctor if you have asthma, kidney disease, a latex allergy, a weak immune system, an active or chronic infection, or signs of infection such as fever, chills, or open sores on your skin.

Anakinra can lower blood cells that help your body fight infections. Your blood may need to be tested often. Avoid being near people who are sick or have infections. Stop using this medicine and call your doctor right away if you have signs of infection such as: fever, chills, flu symptoms, mouth sores, weight loss, or feeling tired or short of breath.

You may have a higher risk of infection if you are also using adalimumab (Humira), certolizumab (Cimzia), etanercept (Enbrel), golimumab (Simponi), infliximab (Remicade), adalimumab (Humira), cancer medicines, steroids, or medicines to prevent organ transplant rejection.

Do not give this medication to anyone under 18 years old without medical advice.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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