Brand Names: Endodan, Percodan
Generic Name: aspirin and oxycodone
- What is aspirin and oxycodone (Endodan, Percodan)?
- What are the possible side effects of aspirin and oxycodone (Endodan, Percodan)?
- What is the most important information I should know about aspirin and oxycodone (Endodan, Percodan)?
- What should I discuss with my healthcare provider before taking aspirin and oxycodone (Endodan, Percodan)?
- How should I take aspirin and oxycodone (Endodan, Percodan)?
- What happens if I miss a dose (Endodan, Percodan)?
- What happens if I overdose (Endodan, Percodan)?
- What should I avoid while taking aspirin and oxycodone (Endodan, Percodan)?
- What other drugs will affect aspirin and oxycodone (Endodan, Percodan)?
- Where can I get more information (Endodan, Percodan)?
What is aspirin and oxycodone (Endodan, Percodan)?
Aspirin and oxycodone is a combination opioid medicine that is used to relieve moderate to severe pain.
Aspirin and oxycodone may also be used for purposes not listed in this medication guide.
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What are the possible side effects of aspirin and oxycodone (Endodan, Percodan)?
Get emergency medical help if you have signs of an allergic reaction: hives, rash; fever, difficulty breathing; swelling of your face, lips, tongue, or throat.
Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
Call your doctor at once if you have:
- weak or shallow breathing, breathing that stops during sleep;
- severe constipation;
- confusion, unusual thoughts or behavior, feeling like you might pass out;
- signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or
- low cortisol levels--nausea, vomiting, loss of appetite, dizziness, feeling weak or tired.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.
Common side effects may include:
- stomach pain, nausea, vomiting, constipation;
- headache, dizziness, drowsiness, tiredness;
- rash; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about aspirin and oxycodone (Endodan, Percodan)?
MISUSE OF OPIOID MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.
Taking opioid medicine during pregnancy may cause life-threatening withdrawal symptoms in the newborn.
Fatal side effects may occur if you use also use alcohol or other drugs that cause drowsiness or slow breathing.
What should I discuss with my healthcare provider before taking aspirin and oxycodone (Endodan, Percodan)?
You should not take this medicine if you are allergic to aspirin or oxycodone, or if you have:
- severe asthma or breathing problems;
- hemophilia (a bleeding disorder); or
- a stomach or bowel obstruction (including paralytic ileus).
Do not give this medicine to a child. Using this medicine in a child or teenager with flu symptoms or chickenpox can cause a serious or fatal condition called Reye's syndrome.
Tell your doctor if you have ever had:
- breathing problems, sleep apnea;
- urination problems;
- a head injury or seizures;
- liver or kidney disease;
- alcoholism, drug addiction, mental illness; or
- problems with your gallbladder, pancreas, thyroid, or adrenal gland.
If you use this medicine during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks. You should not use aspirin and oxycodone after 30 weeks of pregnancy.
Ask a doctor if it is safe to breastfeed. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.
How should I take aspirin and oxycodone (Endodan, Percodan)?
Follow the directions on your prescription label and read all medication guides. Never use aspirin and oxycodone in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of this medicine.
Never share opioid medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away opioid medicine is against the law.
Aspirin and oxycodone may be taken with food if it upsets your stomach.
Tell your doctor if you have a planned surgery.
Do not stop using aspirin and oxycodone suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.
Store at room temperature away from moisture, heat, and light.
Do not keep leftover opioid medication. Just one dose can cause death in someone using this medicine accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush the unused medicine down the toilet.
What happens if I miss a dose (Endodan, Percodan)?
Since aspirin and oxycodone is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next dose. Do not use two doses at one time.
What happens if I overdose (Endodan, Percodan)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An opioid overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.
Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.
Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.
What should I avoid while taking aspirin and oxycodone (Endodan, Percodan)?
Do not drink alcohol. Dangerous side effects or death could occur.
Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to aspirin (such as aspirin, ibuprofen, ketoprofen, or naproxen).
What other drugs will affect aspirin and oxycodone (Endodan, Percodan)?
You may have breathing problems or withdrawal symptoms if you start or stop taking certain other medicines, especially an antibiotic, antifungal medication, heart or blood pressure medication, seizure medication, or medicine to treat HIV or hepatitis C.
Opioid medicine can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:
- cold or allergy medicines, bronchodilator asthma/COPD medication, or a diuretic ("water pill");
- medicines for motion sickness, irritable bowel syndrome, or overactive bladder;
- other narcotic medications--opioid pain medicine or prescription cough medicine;
- a sedative like Valium--diazepam, alprazolam, lorazepam, Xanax, Klonopin, Versed, and others;
- drugs that make you sleepy or slow your breathing--a sleeping pill, muscle relaxer, medicine to treat mood disorders or mental illness; or
- drugs that affect serotonin levels in your body--a stimulant, or medicine for depression, Parkinson's disease, migraine headaches, serious infections, or nausea and vomiting.
This list is not complete. Other drugs may affect aspirin and oxycodone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.
Where can I get more information (Endodan, Percodan)?
Your doctor or pharmacist can provide more information about aspirin and oxycodone.
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