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Medications and Drugs

Brand Names: Aspirin

Generic Name: aspirin (rectal) (Pronunciation: AS pi rin)

What is rectal aspirin (Aspirin)?

Aspirin is in a group of drugs called salicylates. It works by reducing substances in the body that cause pain and inflammation. Aspirin also reduces fever.

Rectal aspirin is given as a suppository to reduce pain, inflammation, and fever. Aspirin is also used to treat the symptoms of arthritis and rheumatic fever.

Rectal aspirin may also be used for purposes not listed in this medication guide.

What are the possible side effects of rectal aspirin (Aspirin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have a serious side effect such as:

  • black, bloody, or tarry stools;
  • blood in your urine;
  • coughing up blood or vomit that looks like coffee grounds;
  • pale skin, easy bruising or bleeding;
  • wheezing, chest tightness, trouble breathing;
  • decreased hearing or ringing in the ears;
  • seizure (convulsions); or
  • dizziness, confusion, or hallucinations.

Less serious side effects may include:

  • nausea, vomiting, stomach pain; or
  • rectal irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about rectal aspirin (Aspirin)?

Rectal aspirin should not be used in a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin can cause a serious and sometimes fatal condition called Reye's syndrome.

Do not take an aspirin rectal suppository by mouth. It is for use only in your rectum.

This medication comes with patient instructions for using the rectal suppository. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Try to empty your bowel and bladder just before using the aspirin suppository.

Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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