baloxavir marboxil (Xofluza)

Brand Names: Xofluza

Generic Name: baloxavir marboxil

What is baloxavir marboxil (Xofluza)?

Baloxavir marboxil is used to treat flu symptoms caused by influenza virus in people who have had symptoms for no more than 48 hours. Baloxavir marboxil will not treat the common cold.

Baloxavir marboxil is for adults and children who are at least 12 years old and weigh at least 88 pounds (40 kilograms).

Baloxavir marboxil should not be used in place of getting a yearly flu shot. The Centers for Disease Control and Prevention recommends an annual flu shot to help protect you each year from new strains of influenza virus.

Baloxavir marboxil may also be used for purposes not listed in this medication guide.

What are the possible side effects of baloxavir marboxil (Xofluza)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about baloxavir marboxil (Xofluza)?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What should I discuss with my healthcare provider before taking baloxavir marboxil (Xofluza)?

You should not use baloxavir marboxil if you are allergic to it.

Tell your doctor if you are pregnant or breast-feeding.

It is not known whether this medicine will harm an unborn baby. However, having influenza during pregnancy can cause severe complications that could harm both mother and baby. The benefit of using baloxavir marboxil to treat flu symptoms may outweigh any risks.

The Centers for Disease Control and Prevention recommends that pregnant women get a flu shot during any trimester of pregnancy to protect themselves and their newborn babies from flu.

How should I take baloxavir marboxil (Xofluza)?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Baloxavir marboxil is usually given as a single dose of 1 or more tablets to be taken at one time.

Take baloxavir marboxil when you first notice flu symptoms (fever, chills, muscle aches, sore throat, runny or stuffy nose). This medicine may not be effective if you have been sick for longer than 48 hours.

You may take baloxavir marboxil with or without food.

Do not take this medicine with dairy products such as milk or yogurt, or with calcium-fortified juice.

Also avoid taking baloxavir marboxil with a laxative, antacid, or vitamin/mineral supplement that contains calcium, magnesium, iron, selenium, or zinc.

Call your doctor if your symptoms do not improve, or if they get worse.

Store tablets in the blister pack at room temperature, away from moisture and heat.


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What happens if I miss a dose (Xofluza)?

Baloxavir marboxil is used as a single dose and does not have a daily dosing schedule.

What happens if I overdose (Xofluza)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid after taking baloxavir marboxil (Xofluza)?

Ask your doctor before getting a "live" flu vaccine (such as nasal FluMist). Baloxavir marboxil may interfere with the drug action of FluMist, making the vaccine less effective.

What other drugs will affect baloxavir marboxil (Xofluza)?

Other drugs may affect baloxavir marboxil, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information (Xofluza)?

Your pharmacist can provide more information about baloxavir marboxil.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Reviewed on 10/12/2022

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