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Medications and Drugs

Brand Names: Cogentin

Generic Name: benztropine (Pronunciation: BENZ troe peen)

What is benztropine (Cogentin)?

Benztropine reduces the effects of certain chemicals in the body that may become unbalanced as a result of disease (such as Parkinson's), drug therapy, or other causes.

Benztropine is used to treat the symptoms of Parkinson's disease, such as muscle spasms, stiffness, tremors, sweating, drooling, and poor muscle control.

Benztropine is also used to treat and prevent these symptoms when they are caused by drugs such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), and others.

Benztropine may also be used for purposes not listed in this medication guide.

Benztropine 0.5 mg-IVA

round, white, imprinted with par 164

Benztropine 0.5 mg-UPS

round, white, imprinted with 832 BM 05

Benztropine 1 mg-IVA

oval, white, imprinted with par 165

Benztropine 1 mg-ROS

elliptical, white, imprinted with 832 BM1

Benztropine 2 mg-PAR

round, white, imprinted with par 166

Benztropine 2 mg-UPS

round, white, imprinted with 832 BM2

What are the possible side effects of benztropine (Cogentin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • pounding heartbeats or fluttering in your chest;
  • feeling very weak;
  • feeling too weak to move;
  • confusion, hallucinations, unusual thoughts or behavior;
  • urinating less than usual or not at all;
  • severe constipation;
  • dry mouth that interferes with speech, swallowing, appetite, or eating;
  • feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
  • blurred vision, eye pain, or seeing halos around lights; or
  • twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs.

Less serious side effects may include:

  • depressed mood, memory problems;
  • drowsiness, feeling nervous or excited;
  • nausea, upset stomach;
  • dry mouth (mild);
  • double vision, increased sensitivity to light; or
  • numbness in your fingers;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about benztropine (Cogentin)?

You should not take this medication if you are allergic to benztropine, or if you are also taking a medication called pramlintide (Symlin).

Before you take benztropine, tell if you have glaucoma, kidney or liver disease, heart disease, high blood pressure, a history of heart attack or stroke, a breathing disorder, a nerve or muscle disorder, seizures, urination problems, overactive thyroid, mental illness, or a stomach or intestinal disorder.

Avoid taking a diarrhea medication or antacid within 2 hours before or after you take benztropine. Also avoid taking ketoconazole (Nizoral) within 2 hours after you take benztropine.

Benztropine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Benztropine can decrease perspiration and you may be more prone to heat stroke.

Do not stop taking this medication without first talking to your doctor. Stopping suddenly may make your condition worse. You may need to use less and less before you stop the medication completely.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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