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Medications and Drugs

Brand Names: Bumex

Generic Name: bumetanide (Pronunciation: byoo MET a nide)

What is bumetanide (Bumex)?

Bumetanide is a loop diuretic (water pill) that prevents your body from absorbing too much salt, allowing the salt to instead be passed in your urine.

Bumetanide treats fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome.

Bumetanide may also be used for other purposes not listed in this medication guide.

Bumetanide 0.5 mg -ZEN

round, green, imprinted with 0.5, Z 4232

Bumetanide 0.5 mg-EON

round, green, imprinted with E 128

Bumetanide 0.5 mg-MYL

round, green, imprinted with E 128

Bumetanide 0.5 mg-TEV

round, green, imprinted with Z 4232, 0.5

Bumetanide 1 mg-EON

round, yellow, imprinted with E 129

Bumetanide 1 mg-MYL

round, yellow, imprinted with E 129

Bumetanide 1 mg-TEV

round, yellow, imprinted with Z 4233, 1

Bumetanide 1 mg-ZEN

round, yellow, imprinted with Z 4233, 1

Bumetanide 2 mg-EON

round, beige, imprinted with E 130

Bumetanide 2 mg-TEV

round, pink, imprinted with Z 4234, 2

Bumetanide 2mg-ZEN

round, peach, imprinted with Z 4234, 2

Bumex 0.5 mg

oval, green, imprinted with ROCHE, BUMEX0.5

Bumex 1 mg

elliptical, yellow, imprinted with ROCHE, BUMEX 1

Bumex 2 mg

oval, peach, imprinted with BUMEX 2, ROCHE

What are the possible side effects of bumetanide

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using bumetanide and call your doctor at once if you have a serious side effect such as:

  • feeling like you might pass out;
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);
  • headache, trouble concentrating, memory problems, weakness, loss of appetite, feeling unsteady, hallucinations, seizure, shallow breathing or breathing that stops;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
  • hearing problems.

Less serious side effects may include:

  • mild muscle pain;
  • dizziness;
  • headache;
  • stomach pain, mild nausea; or
  • mild itching or skin rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about bumetanide (Bumex)?

You should not use bumetanide if you are allergic to it, if you are unable to urinate, if you have severe kidney or liver disease, or if you are severely dehydrated.

Before you take bumetanide, tell your doctor if you have kidney or liver disease, gout, diabetes, or an allergy to sulfa drugs.

To be sure this medication is not causing harmful effects, your blood may need to be tested often. Your kidney or liver function may also need to be tested. Visit your doctor regularly.

Bumetanide will make you urinate more often and you may get dehydrated easily. Follow your doctor's instructions about using potassium supplements or getting enough salt and potassium in your diet.

Avoid becoming dehydrated. Follow your doctor's instructions about the type and amount of liquids you should drink while you are taking bumetanide.

There are many other drugs that can interact with bumetanide (including some over-the-counter medicines). Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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