calcifediol (Rayaldee)

Brand Names: Rayaldee

Generic Name: calcifediol

What is calcifediol (Rayaldee)?

Calcifediol is a vitamin D3. Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Calcifediol is used to treat hyperparathyroidism (overactive parathyroid glands) in people who have stage 3 or 4 chronic kidney failure and low vitamin D levels. Calcifediol is not for people who are receiving dialysis.

Calcifediol may also be used for purposes not listed in this medication guide.

What are the possible side effects of calcifediol (Rayaldee)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about calcifediol (Rayaldee)?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What should I discuss with my healthcare provider before taking calcifediol (Rayaldee)?

Tell your doctor if you have ever had:

  • heart problems; or
  • high levels of calcium in your blood (hypercalcemia).

Tell your doctor if you are pregnant or plan to become pregnant. It is not known whether calcifediol will harm an unborn baby. However, having chronic kidney disease during pregnancy may cause complications such as miscarriage, premature birth, low birth weight, stillbirth, or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of treating kidney disease may outweigh any risks to the baby.

If you are breastfeeding, tell your doctor if you notice including vomiting, constipation, weight loss, or seizures in the nursing baby.

How should I take calcifediol (Rayaldee)?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take this medicine at bedtime each day.

Swallow the capsule whole and do not crush, chew, break, or open it.

You will need frequent medical tests.

Store at room temperature away from moisture and heat.

SLIDESHOW

Hyperthyroidism Symptoms and Treatment See Slideshow

What happens if I miss a dose (Rayaldee)?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose (Rayaldee)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include vomiting, constipation, loss of appetite, feeling tired or irritable, muscle weakness, feeling very thirsty or hot, or urinating less than usual.

What should I avoid while taking calcifediol (Rayaldee)?

Ask a doctor or pharmacist before using any vitamins or mineral supplements. Many non-prescription dietary supplements contain calcium or vitamin D. Taking certain products together can cause you to get too much of these ingredients.

What other drugs will affect calcifediol (Rayaldee)?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your other medicines, especially:

This list is not complete and many other drugs may affect calcifediol. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information (Rayaldee)?

Your pharmacist can provide more information about calcifediol.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Reviewed on 7/12/2021

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