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cefazolin (cont.)

What should I discuss with my health care provider before using cefazolin (Ancef, Kefzol)?

You should not use this medication if you have ever had a severe allergic reaction to cefazolin or any other cephalosporin antibiotic, such as:

To make sure you can safely use cefazolin, tell your doctor if you have any of these other conditions:

  • kidney disease;
  • liver disease;
  • a stomach or intestinal disorder such as colitis; or
  • if you are allergic to any type of penicillin.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Cefazolin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use cefazolin (Ancef, Kefzol)?

Cefazolin is injected into a muscle or into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, syringes, IV tubing, and other items used to inject the medicine.

Cefazolin must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medication.

Prepare your dose in a syringe only when you are ready to give yourself an injection.

Shake the mixture well just before you measure a dose. Do not use the medication if it has changed colors or has particles in it. Call your doctor for a new prescription.

Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Cefazolin will not treat a viral infection such as the common cold or flu.

This medication can cause you to have unusual results with certain lab tests to check for glucose (sugar) in the urine. Tell any doctor who treats you that you are using cefazolin.

Store unmixed cefazolin dry powder at room temperature, away from moisture, heat, and light.

After mixing cefazolin with a diluent, you may store the mixture in the refrigerator and use it within 7 to 10 days. Do not freeze. Follow the storage directions on your medicine label.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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