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celecoxib (CeleBREX)

Brand Names: CeleBREX

Generic Name: celecoxib

What is celecoxib (CeleBREX)?

Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID).

Celecoxib is used to treat pain or inflammation caused by many conditions such as arthritis, ankylosing spondylitis, and menstrual pain. Celecoxib is used to treat juvenile rheumatoid arthritis in children who are at least 2 years old. Celecoxib is also used in the treatment of hereditary polyps in the colon.

Celecoxib may also be used for purposes not listed in this medication guide.

What are the possible side effects of celecoxib (CeleBREX)?

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.

Stop using celecoxib and call your doctor at once if you have:

  • the first sign of any skin rash, no matter how mild;
  • heart problems--swelling, rapid weight gain, feeling short of breath;
  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • liver problems--nausea, stomach pain (upper right side), itching, tiredness, dark urine, jaundice (yellowing of the skin or eyes);
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or
  • low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about celecoxib (CeleBREX)?

Celecoxib can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Celecoxib may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using celecoxib, especially in older adults.

What should I discuss with my healthcare provider before taking celecoxib (CeleBREX)?

Celecoxib can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Celecoxib may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using celecoxib, especially in older adults.

You should not use celecoxib if you are allergic to it, or if you have:

Tell your doctor if you have ever had:

Taking celecoxib during the last 3 months of pregnancy may harm the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

This medicine may affect fertility (ability to have children) in women. Ask your doctor about this risk.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How should I take celecoxib (CeleBREX)?

Follow all directions on your prescription label and read all medication guides. Use the lowest dose that is effective in treating your condition.

You may take celecoxib with or without food.

If you cannot swallow a capsule whole, open it and sprinkle the medicine into a spoonful of applesauce. Swallow the mixture with water. You may save this applesauce mixture for later use in a refrigerator for up to 6 hours.

Store at room temperature away from moisture and heat.

QUESTION

The term arthritis refers to stiffness in the joints. See Answer

What happens if I miss a dose (CeleBREX)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose (CeleBREX)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking celecoxib (CeleBREX)?

Avoid taking aspirin or other NSAIDs while you are taking celecoxib.

Avoid drinking alcohol. It may increase your risk of stomach bleeding.

Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to celecoxib (such as aspirin, ibuprofen, ketoprofen, or naproxen).

What other drugs will affect celecoxib (CeleBREX)?

Ask your doctor before using celecoxib if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.

Many drugs can affect celecoxib. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information (CeleBREX)?

Your pharmacist can provide more information about celecoxib.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Reviewed on 7/24/2019

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