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Medications and Drugs

Brand Names: Chlo Tuss EX, Vanacof G

Generic Name: chlophedianol and guaifenesin (Pronunciation: KLOE fe DYE a nol and gwye FEN e sin)

What is chlophedianol and guaifenesin (Chlo Tuss EX, Vanacof G)?

Chlophedianol is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

The combination of chlophedianol and guaifenesin is used to treat cough and chest congestion caused by the common cold or flu.

Chlophedianol and guaifenesin will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlophedianol and guaifenesin may also be used for purposes not listed in this medication guide.

What are the possible side effects of chlophedianol and guaifenesin (Chlo Tuss EX, Vanacof G)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using chlophedianol and guaifenesin and call your doctor at once if you have a serious side effect such as:

Less serious side effects may include:

  • mild dizziness or drowsiness;
  • mild headache;
  • diarrhea, nausea, upset stomach;
  • sleep problems (insomnia); or
  • feeling nervous, restless, or anxious.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about chlophedianol and guaifenesin (Chlo Tuss EX, Vanacof G)?

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Do not use cough or cold medicine if you have untreated or uncontrolled breathing disorder such as asthma, emphysema, or chronic bronchitis.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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