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choline magnesium trisalicylate (Choline Magnesium Trisalicylate, CMT, Tricosal)

Brand Names: Choline Magnesium Trisalicylate, CMT, Tricosal, Trilisate

Generic Name: choline magnesium trisalicylate

What is choline magnesium trisalicylate?

Choline magnesium trisalicylate is a non-steroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain, fever, and inflammation.

Choline magnesium trisalicylate is used to treat mild-to-moderate pain, fever, inflammatory conditions, and pain, swelling, or stiffness associated with arthritis. This medicine is also used to reduce fever in adults.

Choline magnesium trisalicylate may also be used for purposes not listed in this medication guide.

What are the possible side effects of choline magnesium trisalicylate?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using choline magnesium trisalicylate and call your doctor at once if you have:

  • trouble breathing;
  • ringing in your ears, hearing loss;
  • behavior changes with nausea and vomiting in a child using this medicine;
  • worsening fever or pain; or
  • signs of stomach bleeding--feeling light-headed, ongoing stomach pain, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about choline magnesium trisalicylate?

Do not take more of this medicine than recommended on the label. An overdose of choline magnesium trisalicylate can be fatal.

You should not use this medicine if you are allergic to salicylates (such as aspirin) or other nonsteroidal anti-inflammatory drugs (NSAIDs).

Choline magnesium trisalicylate may cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using choline magnesium trisalicylate, especially in older adults.

Do not give this medicine to a child or teenager with a fever, flu symptoms, or chicken pox. Salicylates can cause Reye's syndrome, a serious and sometimes fatal condition in children.

What should I discuss with my healthcare provider before taking choline magnesium trisalicylate?

You should not use choline magnesium trisalicylate if you are allergic to it, or if you have ever had:

Do not give this medicine to a child or teenager with a fever, flu symptoms, or chicken pox. Salicylates can cause Reye's syndrome, a serious and sometimes fatal condition in children.

Choline magnesium trisalicylate may cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using choline magnesium trisalicylate, especially in older adults.

To make sure choline magnesium trisalicylate is safe for you, tell your doctor if you have ever had:

Taking choline magnesium trisalicylate during late pregnancy may cause bleeding in the mother or the baby during delivery. Tell your doctor if you are pregnant or plan to become pregnant.

Choline magnesium trisalicylate can pass into breast milk and may cause side effects in the nursing baby. Tell your doctor if you are breast-feeding.

How should I take choline magnesium trisalicylate?

This medicine is usually given 2 to 3 times per day. Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Take this medicine with a full glass of water.

Take with food if choline magnesium trisalicylate upsets your stomach.

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

If a child is using this medicine, tell your doctor if the child has any changes in weight. Choline magnesium trisalicylate doses are based on weight in children, and any changes may affect your child's dose.

While using choline magnesium trisalicylate, you may need frequent blood tests.

If you need surgery, tell the surgeon ahead of time that you are using choline magnesium trisalicylate. You may need to stop using the medicine for a short time.

This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using choline magnesium trisalicylate.

It may take up to 3 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of choline magnesium trisalicylate can be fatal.

Overdose symptoms may include vomiting, diarrhea, sweating more than usual, ringing in your ears, confusion, trouble breathing, and severe dizziness or drowsiness.

What should I avoid while taking choline magnesium trisalicylate?

Drinking alcohol may increase your risk of stomach bleeding.

Smoking can also increase your risk of stomach bleeding.

Ask a doctor or pharmacist before using any cold, allergy, or pain medicine. Many medicines available over the counter contain salicylates or NSAIDs. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains aspirin, ibuprofen, ketoprofen, naproxen, or a salicylate.

What other drugs will affect choline magnesium trisalicylate?

Tell your doctor about all your current medicines and any you start or stop using, especially:

This list is not complete. Other drugs may interact with choline magnesium trisalicylate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your pharmacist can provide more information about choline magnesium trisalicylate.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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