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Medications and Drugs

Brand Names: Cyclomydril

Generic Name: cyclopentolate and phenylephrine ophthalmic (Pronunciation: SYE kloe PEN toe late and FEN il EFF rin off THAL mik)

What is cyclopentolate and phenylephrine ophthalmic (Cyclomydril)?

Cyclopentolate and phenylephrine relaxes muscles in your eye to dilate (widen) your pupil.

Cyclopentolate and phenylephrine ophthalmic (for the eye) is used to dilate your pupil in preparation for an eye exam.

Cyclopentolate and phenylephrine ophthalmic may also be used for other purposes not listed in this medication guide.

What are the possible side effects of cyclopentolate and phenylephrine ophthalmic (Cyclomydril)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your doctor at once if you have severe burning, stinging, or irritation in your eyes.

Less serious side effects may include:

  • mild stinging in your eyes;
  • dry mouth, nose, or throat;
  • decreased sweating; or
  • sensitivity to sunlight.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about cyclopentolate and phenylephrine ophthalmic (Cyclomydril)?

You should not receive this medication if you are allergic to cyclopentolate or phenylephrine, or if you have narrow-angle glaucoma.

Do not use this medication if you have taken an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 10 days.

Before you receive this medication, tell your doctor if you have heart disease, high blood pressure, or overactive thyroid.

Also tell your doctor if you are also taking guanethidine (Ismelin), reserpine, methyldopa (Aldomet), or an antidepressant (Elavil, Tofranil, Norpramin, and others.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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