dextromethorphan and guaifenesin (Adult Cough DM, Allfen DM, Altarussin DM)

Brand Names: Adult Cough DM, Allfen DM, Altarussin DM, Amibid DM, Anti-Tuss DM, Aquabid DM, Aquatab DM, Aquatab DM(obsolete), Benylin Expectorant, Bidex-DM, Bidex-DMI, Biotuss DM, Broncotron, Cheracol D Cough, Cheracol-D, Children Giltuss Cough & Chest Congestion, Children's Delsym Cough+Chest Congest DM, Children's Mucus Relief Cough, Children's Robitussin Cough & Chest Congestion DM, Children's Robitussin Cough and Chest, Children's Triaminic Cough and Congestion, Congesta DM, Coricidin HBP Chest Congestion & Cough, Cough Formula-DM, Creo-Terpin, DayQuil Mucus Control DM, Delsym Cough Plus Chest Congestion DM, Dex-Tuss DM, Diabetic Suppressant, Diabetic Tuss DM, Diabetic Tuss DM Maximum Strength, Diabetic Tussin DM, Double-Tussin DM, DuraDEX, Duraganidin, Fenesin DM, Fenesin DM IR, Fenex-DM, G Bid DM, Gani-Tuss-DM NR, G-Bid DM, Genatuss DM, GG/DM, GG-DM SR, Giltuss Cough & Chest Congestion, Giltuss Diabetic Cough & Cold, G-Tron, Guaiasorb Cough Medicine, Guaiasorb DM, Guai-Dex, Guaifen DM, GuaiFENesin DM, GuaiFENesin DM NR, GuaiFENesin DM SR, Guaifenex DM, Guiacough DM, Guiadrine DM, Guiat Clear DM, Guiatuss Clear, Guiatuss DM, Guiatussin-DM, G-Zyncof, Halotussin DM, Halotussin DM Sugar Free, Humibid CS, Humigen DM, Iobid DM, Iofen-DM NF, Iophen DM, Iophen DM NR, Kita La Tos, Kolephrin GG/DM, Lotussin DM, Mastussin DM, Maximum Strength Mucus DM, Mintab DM, Monafed DM, Mucinex Children's Cough, Mucinex Children's Cough Mini-Melts, Mucinex Children's FreeFrom Cough & Mucus, Mucinex DM, Mucinex DM Maximum Strength, Mucinex Fast-Max DM Max, Mucobid DM, Muco-Fen DM, Mucus DM, Mucus Relief DM, Mytussin DM, Naldecon DX Liquigel, Naldecon Senior DX, Nalspan Senior DX, Pecgen DMX, Phanatuss, Phlemex, Q-Bid DM, Q-Tussin DM, Recofen D, Recofen Plus, Respa-DM, Rhinosyn-DMX, Ri-Tussin DM, Robafen DM, Robafen DM Clear, Robafen DM Cough & Chest Congestion, Robafen DM Max, Robichem DM, Robitussin Cough & Congestion, Robitussin Cough & Congestion DM Max, Robitussin Cough + Chest Congestion DM, Robitussin Cough + Chest Congestion DM Maximum Strength, Robitussin Cough + Chest Congestion DM Peak Cold, Robitussin Cough + Chest Congestion DM Peak Cold Sugar-Free, Robitussin Cough+Chest Cong DM, Robitussin DM (obsolete), Robitussin DM Sugar Free, Robitussin DM To Go, Robitussin Peak Cold Max Strength Cough+Chest Congestion DM, Robitussin-SF, Safetussin 30 DM, Safetussin DM, Scot-Tussin DM, Scot-Tussin Senior, Siltussin DM, Siltussin DM DAS Cough Formula, Siltussin-DM DAS-NA, Siltussin-DM DAS-NA Maximum Strength, S-Pack DM, TabTussin DM, Tolu-Sed DM, Touro DM, Trispec DMX, T-Tussin DM, Tusnel Diabetic, Tusscidin DM, Tussi-Bid, Tussidin DM, Tussin Cough, Tussin DM, Tussin DM Max, Tussi-Organidin DM NR, Tussi-Organidin DM NR(obsolete), Tussi-Organidin DM-S NR, Tussi-Organidin DM-S NR (obsolete), Vicks 44E, Vicks 44E Pediatric, Zyncof

Generic Name: dextromethorphan and guaifenesin

What is dextromethorphan and guaifenesin?

Dextromethorphan is a cough suppressant. Guaifenesin is an expectorant.

Dextromethorphan and guaifenesin is a combination medicine used to treat cough and chest congestion caused by the common cold or allergies.

Dextromethorphan will not treat a cough that is caused by smoking.

There are many brands and forms of this medication available and not all brands are listed on this leaflet.

Dextromethorphan and guaifenesin may also be used for purposes not listed in this medication guide.

What are the possible side effects of dextromethorphan and guaifenesin?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about dextromethorphan and guaifenesin?

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

What should I discuss with my healthcare provider before taking dextromethorphan and guaifenesin?

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, and tranylcypromine.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

Ask a doctor before using this medicine if you are pregnant or breast-feeding.

This medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).

How should I take dextromethorphan and guaifenesin?

Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use until your symptoms clear up.

Always follow directions on the medicine label about giving cough or cold medicine to a child. Do not use the medicine only to make a child sleepy. Death can occur from the misuse of cough or cold medicines in very young children.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

You may need to shake the liquid before you measure a dose. Follow all directions on the label.

Swallow the extended-release tablet whole and do not crush, chew, or break it.

Sprinkle the granules directly onto your tongue and swallow right away.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medicine.

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat.


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What happens if I miss a dose?

Since dextromethorphan and guaifenesin is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking dextromethorphan and guaifenesin?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Drinking alcohol with this medicine can cause side effects.

Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.

What other drugs will affect dextromethorphan and guaifenesin?

Avoid using this medicine with other drugs that cause drowsiness or slow your breathing (such as opioid medicine, a muscle relaxer, or medicine for anxiety or seizures).

Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your pharmacist can provide more information about dextromethorphan and guaifenesin.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Reviewed on 10/12/2022

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