dostarlimab (Jemperli)

Brand Names: Jemperli

Generic Name: dostarlimab

What is dostarlimab (Jemperli)?

Dostarlimab is used to treat a certain type of uterine cancer after other treatments did not work or stopped working.

Your doctor will make sure you have the correct tumor type to be treated with dostarlimab.

Dostarlimab may also be used for purposes not listed in this medication guide.

What are the possible side effects of dostarlimab (Jemperli)?

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Some side effects may occur during the injection. Tell your caregiver if you feel light-headed, chilled or feverish, itchy, or short of breath.

Dostarlimab strengthens your immune system to help it attack cancer cells, but it may also attack healthy cells and you could develop serious or fatal side effects.

Call your doctor at once if you have:

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about dostarlimab (Jemperli)?

Call your doctor at once if you have new or worsening symptoms such as: cough, chest pain, breathing problems, severe stomach pain, diarrhea, bloody or tarry stools, headaches, confusion, severe weakness, vision problems, decreased urination, bruising or bleeding, blood in your urine, dark urine, or yellowing of the skin or eyes.

What should I discuss with my healthcare provider before receiving dostarlimab (Jemperli)?

Tell your doctor if you have ever had:

  • breathing problems; or
  • immune system problems.

May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use birth control while using dostarlimab and for at least 4 months after your last dose. Tell your doctor if you become pregnant.

Do not breastfeed while using this medicine, and for at least 4 months after your last dose.

How is dostarlimab given (Jemperli)?

Dostarlimab is injected into a vein by a healthcare provider. This medicine is injected slowly over 30 minutes.

Dostarlimab is usually given every 3 weeks at first, and then every 6 weeks.

You may need medical tests to help determine how long you should use dostarlimab.


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What happens if I miss a dose (Jemperli)?

Call your doctor for instructions if you miss an appointment for your dostarlimab injection.

What happens if I overdose (Jemperli)?

Since this medicine is given in a medical setting, an overdose is unlikely.

What should I avoid while receiving dostarlimab (Jemperli)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect dostarlimab (Jemperli)?

Other drugs may affect dostarlimab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information (Jemperli)?

Your pharmacist can provide more information about dostarlimab.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Reviewed on 3/17/2022

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