ecallantide (Kalbitor)

Brand Names: Kalbitor

Generic Name: ecallantide

What is ecallantide (Kalbitor)?

Ecallantide is used to treat attacks of hereditary angioedema (an immune system disorder). This medicine is for use in adults and children at least 12 years old.

Ecallantide is not a cure for hereditary angioedema.

Ecallantide may also be used for purposes not listed in this medication guide.

What are the possible side effects of ecallantide (Kalbitor)?

Ecallantide can cause a serious allergic reaction within 1 hour after injection. Tell your caregivers right away if you have:

  • chest pain or tightness, fast or weak heartbeat;
  • wheezing, cough, throat irritation, trouble breathing;
  • hoarse voice, tight feeling in your throat, trouble swallowing;
  • swelling of your lips, tongue, or throat;
  • swelling or redness in your face;
  • itching, rash, or hives;
  • flushing (warmth, redness, or tingly feeling);
  • sneezing, runny or stuffy nose; or
  • dizziness, feeling like you might pass out.

An allergic reaction may have the same symptoms as hereditary angioedema. Your caregivers will watch you closely and will quickly treat an allergic reaction.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about ecallantide (Kalbitor)?

Ecallantide can cause a serious allergic reaction within 1 hour after injection. Symptoms include wheezing, cough, trouble breathing or swallowing, itching, hives, dizziness, fainting, or swelling in your face or throat.

What should I discuss with my health care provider before receiving ecallantide (Kalbitor)?

If possible during an emergency, tell your caregivers you have any type of allergy. Make sure any follow-up doctor knows you received this medicine.

You should not be treated with ecallantide if you are allergic to it.

If possible during an emergency, tell your caregivers if you are pregnant or breastfeeding.

How is ecallantide given (Kalbitor)?

Ecallantide is injected under the skin by a healthcare provider, usually in 3 separate injections.

You will be watched closely to make sure you do not have an allergic reaction to the medication.

If you still have angioedema symptoms after 3 injections, more may be given within 24 hours.


Heart Disease: Causes of a Heart Attack See Slideshow

What happens if I miss a dose (Kalbitor)?

In a medical setting you are not likely to miss a dose.

What happens if I overdose (Kalbitor)?

In a medical setting an overdose would be treated quickly.

What should I avoid after receiving ecallantide (Kalbitor)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect ecallantide (Kalbitor)?

Other drugs may affect ecallantide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Where can I get more information (Kalbitor)?

Your doctor or pharmacist can provide more information about ecallantide.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Health Solutions From Our Sponsors

Reviewed on 10/12/2022

Health Solutions From Our Sponsors