formoterol and glycopyrrolate (Bevespi Aerosphere)

Brand Names: Bevespi Aerosphere

Generic Name: formoterol and glycopyrrolate

What is formoterol and glycopyrrolate (Bevespi Aerosphere)?

Formoterol and glycopyrrolate is a combination medicine used to prevent airflow obstruction and reduce flare-ups in adults with COPD (chronic obstructive pulmonary disease), including bronchitis and emphysema.

Formoterol and glycopyrrolate may also be used for purposes not listed in this medication guide.

What are the possible side effects of formoterol and glycopyrrolate (Bevespi Aerosphere)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • tremors, nervousness, chest pain, fast or pounding heartbeats;
  • wheezing, choking, or other breathing problems after using this medicine;
  • painful or difficult urination;
  • blurred vision, tunnel vision, eye pain or redness, or seeing halos around lights;
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
  • low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, numbness or tingling, muscle weakness or limp feeling.

Common side effects may include:

  • cough; or
  • urination problems.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about formoterol and glycopyrrolate (Bevespi Aerosphere)?

This medicine is for use only in people with chronic obstructive pulmonary disease (COPD) and should not be used to treat asthma.

Formoterol and glycopyrrolate is not a rescue medicine. It will not work fast enough to treat a bronchospasm attack.

Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working as well.

What should I discuss with my healthcare provider before using formoterol and glycopyrrolate (Bevespi Aerosphere)?

You should not use this medicine if you are allergic to formoterol or glycopyrrolate. This medicine is for use only in people with COPD and should not be used to treat asthma.

Tell your doctor if you have ever had:

Tell your doctor if you are pregnant or breast-feeding.

This medicine is not approved for use by anyone younger than 18 years old.

How should I use formoterol and glycopyrrolate (Bevespi Aerosphere)?

Follow all directions on your prescription label and read all medication guides. Use the medicine exactly as directed. Using too much of this medicine can cause life-threatening side effects.

Read and follow all patient instructions provided with the inhaler device. Ask your doctor or pharmacist if you do not understand these instructions.

Use only the inhaler device provided with your medicine or you may not get the correct dose. Use the new inhaler each time you get your prescription refilled.

Shake the medicine well just before you inhale your dose.

This medicine is not a rescue medicine for bronchospasm attacks. Use only fast-acting inhalation medicine for an attack. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working as well.

You should not stop using formoterol and glycopyrrolate suddenly. Stopping suddenly may make your condition worse.

Store at room temperature away from moisture, heat, and light. Keep the inhaler device in the sealed foil tray until ready to start using it.

Keep away from open flame or high heat. The canister may explode if it gets too hot. Do not puncture or burn an empty inhaler canister.

Throw the inhaler device away 3 months after you have taken it out of the foil pouch, or if the dose indicator shows a zero, whichever comes first.

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What happens if I miss a dose (Bevespi Aerosphere)?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose (Bevespi Aerosphere)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose can cause vomiting, severe constipation, blurred vision, chest pain, heart problems, or fainting.

What should I avoid while using formoterol and glycopyrrolate (Bevespi Aerosphere)?

If this medicine gets in your eyes, rinse them with water and call your doctor if you have ongoing eye redness even after rinsing.

Do not use a second inhaled bronchodilator that contains formoterol or a similar medicine (such as arformoterol, indacaterol, olodaterol, salmeterol, or vilanterol).

What other drugs will affect formoterol and glycopyrrolate (Bevespi Aerosphere)?

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may affect formoterol and glycopyrrolate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information (Bevespi Aerosphere)?

Your pharmacist can provide more information about formoterol and glycopyrrolate.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Reviewed on 7/12/2021

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