Brand Names: Factive
Generic Name: gemifloxacin
- What is gemifloxacin (Factive)?
- What are the possible side effects of gemifloxacin (Factive)?
- What is the most important information I should know about gemifloxacin (Factive)?
- What should I discuss with my healthcare provider before taking gemifloxacin (Factive)?
- How should I take gemifloxacin (Factive)?
- What happens if I miss a dose (Factive)?
- What happens if I overdose (Factive)?
- What should I avoid while taking gemifloxacin (Factive)?
- What other drugs will affect gemifloxacin (Factive)?
- Where can I get more information (Factive)?
What is gemifloxacin (Factive)?
Gemifloxacin is a fluoroquinolone (flor-o-KWIN-o-lone) antibiotic that fights bacteria in the body.
Fluoroquinolone antibiotics can cause serious or disabling side effects. Gemifloxacin should be used only for infections that cannot be treated with a safer antibiotic.
Gemifloxacin may also be used for purposes not listed in this medication guide.
What are the possible side effects of gemifloxacin (Factive)?
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Gemifloxacin may cause swelling or tearing of (rupture) a tendon. Gemifloxacin can also have serious effects on your nerves, and may cause permanent nerve damage. Stop using this medicine and call your doctor at once if you have:
- signs of tendon rupture--sudden pain, swelling, bruising, tenderness, stiffness, movement problems, or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions); or
- nerve symptoms--numbness, tingling, burning pain, or being more sensitive to temperature, light touch, or the sense of your body position.
Stop using gemifloxacin and call your doctor at once if you have:
- severe stomach pain, diarrhea that is watery or bloody;
- fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out);
- a seizure (convulsions);
- changes in mood or behavior--depression, confusion, hallucinations, paranoia, tremors, feeling restless or anxious, unusual thoughts or behavior, insomnia, nightmares;
- increased pressure inside the skull--severe headaches, ringing in your ears, vision problems, pain behind your eyes; or
- liver problems--upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about gemifloxacin (Factive)?
Gemifloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This effect may be more likely to occur if you are over 60, if you use steroid medication, or if you have had a kidney, heart, or lung transplant.
Call your doctor at once if you have sudden pain, swelling, bruising, tenderness, stiffness, or movement problems in any of your joints. Rest the joint until you receive medical care or instructions.
What should I discuss with my healthcare provider before taking gemifloxacin (Factive)?
Gemifloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. This can happen during treatment or up to several months after you stop taking gemifloxacin. Tendon problems may be more likely to occur if you are over 60, if you take steroid medication, or if you have had a kidney, heart, or lung transplant.
To make sure gemifloxacin is safe for you, tell your doctor if you have ever had:
- tendon problems, arthritis or other joint problems;
- slow heartbeats or other heart rhythm disorder (especially if you take medication to treat it);
- long QT syndrome (in you or a family member);
- trouble swallowing pills;
- liver or kidney disease;
- epilepsy or other seizure disorder;
- a nerve disorder;
- low levels of magnesium or potassium in your blood; or
- if you use a blood thinner (warfarin, Coumadin, Jantoven) and have "INR" or prothrombin time tests.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether gemifloxacin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Gemifloxacin is not approved for use by anyone younger than 18 years old.
How should I take gemifloxacin (Factive)?
Gemifloxacin is usually taken once per day for 5 to 7 days. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Take gemifloxacin with water, and drink extra fluids to keep your kidneys working properly while taking this medicine.
Gemifloxacin may be taken with or without food, but take it at the same time each day.
Do not chew a gemifloxacin tablet. Swallow it whole.
Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Gemifloxacin will not treat a viral infection such as the flu or a common cold.
Do not share this medicine with another person, even if they have the same symptoms you have.
Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose (Factive)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Factive)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking gemifloxacin (Factive)?
Do not take gemifloxacin with dairy products such as milk or yogurt, or with calcium-fortified juice. You may eat or drink these products as part of a regular meal, but do not use them alone when taking gemifloxacin. They could make the medication less effective.
Gemifloxacin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
Avoid exposure to sunlight or tanning beds. Gemifloxacin can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Call your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.
What other drugs will affect gemifloxacin (Factive)?
Some medicines can make gemifloxacin much less effective when taken at the same time. If you take any of the following medicines, take your gemifloxacin dose 2 hours before or 3 hours after you take the other medicine:
- antacids that contain magnesium or aluminum (such as Maalox, Mylanta, or Rolaids), or the ulcer medicine sucralfate (Carafate);
- didanosine (Videx) powder or chewable tablets; or
- vitamin or mineral supplements that contain aluminum, iron, magnesium, or zinc.
Tell your doctor about all your current medicines and any you start or stop using, especially:
- a diuretic or "water pill";
- heart rhythm medication;
- medicine to treat depression or mental illness;
- NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others; or
- steroid medicine--prednisone, methylprednisolone, and others.
This list is not complete. Other drugs may interact with gemifloxacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Where can I get more information (Factive)?
Your pharmacist can provide more information about gemifloxacin.
Copyright 1996-2018 Cerner Multum, Inc. Version: 8.01. Revision Date: 12/21/2017.