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Medications and Drugs

Brand Names: Sancuso

Generic Name: granisetron (transdermal) (Pronunciation: gra NIS e tron)

What is transdermal granisetron (Sancuso)?

Granisetron blocks the actions of chemicals in the body that may cause nausea and vomiting.

Granisetron transdermal (skin patch) is used to prevent nausea and vomiting caused by cancer chemotherapy.

Granisetron may also be used for other purposes not listed in this medication guide.

What are the possible side effects of transdermal granisetron (Sancuso)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Remove the skin patch and call your doctor at once if you have a serious side effect such as:

  • severe redness, itching, swelling, or other irritation where the patch is worn;
  • uneven heart rate;
  • fever, pale skin, easy bruising or bleeding; or
  • feeling like you might pass out.

Less serious side effects may include:

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about transdermal granisetron (Sancuso)?

You should not use this medication if you are allergic to granisetron.

Before using granisetron, tell your doctor if you have a stomach or intestinal disorder, if you have recently had stomach or intestinal surgery, or if you have ever had an allergic reaction to any type of medicated skin patch. You may need a dose adjustment or special tests to safely use granisetron.

Avoid exposing the skin patch or your upper arm to sunlight, sunlamps, or tanning beds. Natural or artificial sunlight can cause a skin reaction where the granisetron skin patch is worn. This effect may last for up to 10 days after the patch is removed. Wear protective clothing over your arms while you are wearing the skin patch and for at least 10 days after you remove a patch.

Do not use granisetron during a time when you are not having chemotherapy, unless your doctor has told you to.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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