Brand Names: Sarclisa
Generic Name: isatuximab
- What is isatuximab (Sarclisa)?
- What are the possible side effects of isatuximab (Sarclisa)?
- What is the most important information I should know about isatuximab (Sarclisa)?
- What should I discuss with my healthcare provider before receiving isatuximab (Sarclisa)?
- How is isatuximab given (Sarclisa)?
- What happens if I miss a dose (Sarclisa)?
- What happens if I overdose (Sarclisa)?
- What should I avoid while receiving isatuximab (Sarclisa)?
- What other drugs will affect isatuximab (Sarclisa)?
- Where can I get more information (Sarclisa)?
What is isatuximab (Sarclisa)?
Isatuximab is given after at least two other cancer treatments did not work or have stopped working.
Isatuximab may also be used for purposes not listed in this medication guide.
What are the possible side effects of isatuximab (Sarclisa)?
Call your doctor at once if you have:
- easy bruising, unusual bleeding, purple or red spots under your skin;
- low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough, trouble breathing;
- low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet; or
- symptoms of pneumonia--cough with mucus, chest pain, feeling short of breath.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
- low blood cell counts;
- diarrhea; or
- cold symptoms such as stuffy nose, sneezing, sore throat;
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about isatuximab (Sarclisa)?
What should I discuss with my healthcare provider before receiving isatuximab (Sarclisa)?
You should not be treated with isatuximab if you are allergic to it.
You may need to have a negative pregnancy test before starting this treatment.
You should not use isatuximab together with pomalidomide if you are pregnant or planning to become pregnant. Pomalidomide can cause severe, life-threatening birth defects with just one dose.
Both men and women using pomalidomide should use effective birth control to prevent pregnancy. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using isatuximab and pomalidomide.
You should not breastfeed while using isatuximab.
Using isatuximab may increase your risk of developing other cancers. Ask your doctor about this risk.
How is isatuximab given (Sarclisa)?
Isatuximab is given as an infusion into a vein. A healthcare provider will give you this injection.
You will be watched closely for at least 30 minutes after your first 2 infusions to make sure you do not have an allergic reaction.
Isatuximab is given in a 28-day treatment cycle. You may need to use the medicine only during certain days of each cycle. Your doctor will determine how long to treat you with this medicine.
You may be given other medications to help prevent serious side effects or an allergic reaction. Keep using these medicines for as long as your doctor has prescribed.
Read all medication guides you receive for the other medicines used in combination with isatuximab.
Isatuximab can lower your blood cell counts. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using isatuximab.
If you receive a blood or plasma transfusion, tell the staff that you are being treated with isatuximab.
What happens if I miss a dose (Sarclisa)?
Call your doctor for instructions if you miss an appointment for your isatuximab injection.
What happens if I overdose (Sarclisa)?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid while receiving isatuximab (Sarclisa)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What other drugs will affect isatuximab (Sarclisa)?
Other drugs may affect isatuximab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Where can I get more information (Sarclisa)?
Your pharmacist can provide more information about isatuximab.
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