lanreotide (Somatuline Depot)

Brand Names: Somatuline Depot

Generic Name: lanreotide

• What is lanreotide (Somatuline Depot)?
• What are the possible side effects of lanreotide (Somatuline Depot)?
• What is the most important information I should know about lanreotide (Somatuline Depot)?
• What should I discuss with my healthcare provider before using lanreotide (Somatuline Depot)?
• How is lanreotide given (Somatuline Depot)?
• What happens if I miss a dose (Somatuline Depot)?
• What happens if I overdose (Somatuline Depot)?
• What should I avoid while using lanreotide (Somatuline Depot)?
• What other drugs will affect lanreotide (Somatuline Depot)?
• Where can I get more information (Somatuline Depot)?

Lanreotide lowers many substances in the body such as insulin and glucagon (involved in regulating blood sugar), growth hormone, and chemicals that affect digestion.

Lanreotide is used in adults to treat:

• acromegaly that cannot be treated with surgery or radiation;
• carcinoid syndrome; or
• a certain type of pancreatic or digestive tract tumor that may spread to other parts of the body.

Lanreotide is sometimes given after other treatments have failed.

Lanreotide may also be used for purposes not listed in this medication guide.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• chest pain, slow heartbeats;
• shortness of breath;
• a light-headed feeling, like you might pass out;
• confusion, memory problems;
• feeling very weak or tired;
• a light-headed feeling, like you might pass out;
• low blood sugar--headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky;
• high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor;
• underactive thyroid symptoms--tiredness, depressed mood, dry skin, thinning hair, decreased sweating, weight gain, puffiness in your face, feeling more sensitive to cold temperatures; or
• signs of a gallbladder problem--sudden severe pain in your upper stomach spreading to your back or shoulder (may occur after meals or at night), nausea, fever, chills, yellowing of the skin or eyes.

Common side effects may include:

• headache, pounding in your neck or ears;
• dizziness;
• nausea, vomiting, diarrhea, stomach pain;
• muscle or joint pain;
• headache, dizziness; or
• pain, itching, or a hard lump where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

You should not use lanreotide if you are allergic to it.

Tell your doctor if you have ever had:

• gallbladder disease;
• diabetes (your diabetes medicine may need to be adjusted);
• liver or kidney disease;
• heart disease; or
• a thyroid disorder.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

This medicine may affect fertility (your ability to have children) in women.

You should not breast-feed while using lanreotide and for at least 6 months after your last dose.

Lanreotide is injected under the skin.

A healthcare provider will give you this injection.

Lanreotide is usually given once every 4 weeks. Your doctor may occasionally change how often you receive injections.

Call your doctor if your symptoms do not improve, or if they get worse.

Your blood sugar may need to be checked often, and you may need other blood tests at your doctor's office.

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Call your doctor for instructions if you miss an appointment for your lanreotide injection.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

When you start or stop taking lanreotide, your doctor may need to adjust the doses of any other medicines you take on a regular basis.

Tell your doctor about all your other medicines, especially:

• bromocriptine;
• cyclosporine;
• insulin or oral diabetes medicine; or
• beta-blocker heart or blood pressure medicine (such as atenolol, carvedilol, metoprolol, propranolol, sotalol, and others).

This list is not complete. Other drugs may affect lanreotide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Your doctor or pharmacist can provide more information about lanreotide.

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