Generic Name: levorphanol (oral)
- What is levorphanol?
- What are the possible side effects of levorphanol?
- What is the most important information I should know about levorphanol?
- What should I discuss with my healthcare provider before taking levorphanol?
- How should I take levorphanol?
- What happens if I miss a dose?
- What happens if I overdose?
- What should I avoid while taking levorphanol?
- What other drugs will affect levorphanol?
- Where can I get more information?
What is levorphanol?
Levorphanol is an opioid pain medication, sometimes called a narcotic.
Levorphanol is used to treat moderate to severe pain.
Levorphanol may also be used for purposes not listed in this medication guide.
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What are the possible side effects of levorphanol?
Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
Call your doctor at once if you have:
- noisy breathing, sighing, shallow breathing, breathing that stops during sleep;
- a slow heart rate or weak pulse;
- a light-headed feeling, like you might pass out;
- mood changes, unusual thoughts or behavior;
- severe stomach pain, severe constipation; or
- low cortisol levels-- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, confusion, fever, sweating, fast heart rate, chest pain, feeling short of breath, muscle stiffness, trouble walking, or feeling faint.
Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.
Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent.
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about levorphanol?
MISUSE OF OPIOID MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.
Fatal side effects can occur if you use opioid medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.
What should I discuss with my healthcare provider before taking levorphanol?
You should not use levorphanol if you are allergic to it, or if you have:
- severe asthma or breathing problems; or
- a stomach or bowel obstruction (including paralytic ileus).
Tell your doctor if you have ever had:
- breathing problems, sleep apnea;
- a head injury, or seizures;
- drug or alcohol addiction, or mental illness;
- liver or kidney disease;
- urination problems; or
- problems with your gallbladder, pancreas, or thyroid.
If you use opioid medicine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on opioids may need medical treatment for several weeks.
Do not breastfeed. Levorphanol can pass into breast milk and may cause drowsiness or breathing problems in a nursing baby.
Levorphanol is not approved for use by anyone younger than 18 years old.
How should I take levorphanol?
Follow the directions on your prescription label and read all medication guides. Never use levorphanol in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of this medicine.
Your dose needs may be different if you recently used opioid medicine and your body is tolerant to it (ask your doctor if you're not sure).
Never share opioid medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away opioid medicine is against the law.
Do not stop using levorphanol suddenly after long-term use, or you could have serious withdrawal symptoms. Ask your doctor how to safely stop using this medicine.
Never crush or break a levorphanol pill to inhale the powder or mix it into a liquid to inject the drug into your vein. Doing so could result in death.
Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.
Do not keep leftover opioid medication. Just one dose can cause death in someone using this medicine accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush the unused medicine down the toilet.
What happens if I miss a dose?
Since levorphanol is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A levorphanol overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include slow breathing and heart rate, severe drowsiness, muscle weakness, cold and clammy skin, pinpoint pupils, or coma.
What should I avoid while taking levorphanol?
Do not drink alcohol. Dangerous side effects or death could occur.
Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
What other drugs will affect levorphanol?
Opioid medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:
- cold or allergy medicines, bronchodilator asthma/COPD medication, or a diuretic ("water pill");
- medicines for motion sickness, irritable bowel syndrome, or overactive bladder;
- other narcotic medications--opioid pain medicine or prescription cough medicine;
- a sedative like Valium--diazepam, alprazolam, lorazepam, Xanax, Klonopin, Ativan, and others;
- drugs that make you sleepy or slow your breathing--a sleeping pill, muscle relaxer, medicine to treat mood disorders or mental illness; or
- drugs that affect serotonin levels in your body--a stimulant, or medicine for depression, Parkinson's disease, migraine headaches, serious infections, or nausea and vomiting.
This list is not complete. Other drugs may affect levorphanol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.
Where can I get more information?
Your pharmacist can provide more information about levorphanol.
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