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losartan (Cozaar)

Brand Names: Cozaar

Generic Name: losartan

What is losartan (Cozaar)?

Losartan is an angiotensin II receptor antagonist (sometimes called an ARB blocker).

Losartan is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old. It is also used to lower the risk of stroke in certain people with heart disease.

Losartan is also used to slow long-term kidney damage in people with type 2 diabetes who also have high blood pressure.

Losartan may also be used for purposes not listed in this medication guide.

What are the possible side effects of losartan (Cozaar)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • pain or burning when you urinate;
  • high potassium level--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or
  • kidney problems--little or no urination, rapid weight gain, painful or difficult urination, swelling in your hands, feet, or ankles.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about losartan (Cozaar)?

Do not use if you are pregnant, and tell your doctor right away if you become pregnant. Losartan can cause injury or death to the unborn baby during your second or third trimester.

If you have diabetes, do not use losartan together with any medication that contains aliskiren (a blood pressure medicine).

What should I discuss with my healthcare provider before taking losartan (Cozaar)?

You should not use losartan if you are allergic to it.

If you have diabetes, do not use losartan together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking losartan with aliskiren if you have kidney disease.

Do not use if you are pregnant, and tell your doctor right away if you become pregnant. Losartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

Tell your doctor if you have ever had:

You should not breast-feed while using this medicine.

Losartan is not approved for use by anyone younger than 6 years old.

How should I take losartan (Cozaar)?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take losartan with or without food.

Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking losartan. This can lead to very low blood pressure, a serious electrolyte imbalance, or kidney failure.

Your blood pressure will need to be checked often and you may need other blood and urine tests.

It may take 3 to 6 weeks before your blood pressure is under control. For best results, keep using the medicine as directed. Talk with your doctor if your condition does not improve after 3 weeks of treatment.

If you have high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Store at room temperature away from moisture, heat, and light.

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How to Lower Blood Pressure: Exercise Tips See Slideshow

What happens if I miss a dose (Cozaar)?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose (Cozaar)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking losartan (Cozaar)?

Drinking alcohol can further lower your blood pressure and may increase certain side effects of losartan.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

What other drugs will affect losartan (Cozaar)?

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may affect losartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information (Cozaar)?

Your pharmacist can provide more information about losartan.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Reviewed on 7/24/2019

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