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Medications and Drugs

Brand Names: Zylet

Generic Name: loteprednol and tobramycin ophthalmic (Pronunciation: LOE te PRED nol and TOE bra MYE sin off THAL mik)

What is loteprednol and tobramycin ophthalmic (Zylet)?

Loteprednol is in a class of drugs called corticosteroids. Loteprednol inhibits processes in the body that cause inflammation (swelling). Tobramycin is an antibiotic.

Loteprednol and tobramycin ophthalmic is used to treat eye inflammation caused by surgery, infection, allergies, and other conditions.

Loteprednol and tobramycin ophthalmic may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of loteprednol and tobramycin ophthalmic (Zylet)?

If you experience a rare but serious allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to loteprednol and tobramycin ophthalmic, stop using the medication and seek emergency medical attention.

Serious side effects are not likely to occur with the use of this medication. Rarely, an increase in the pressure inside of the eye, formation of cataracts, or perforation of the cornea have been reported. Talk to your doctor about any possible side effects.

More commonly, some eye burning, stinging, irritation, itching, redness, sensitivity to light, or blurred vision may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about loteprednol and tobramycin ophthalmic (Zylet)?

Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.

Contact your doctor if your symptoms get worse or if you do not see any improvement in the condition after 48 hours.

If you wear contact lenses, remove them before applying loteprednol and tobramycin ophthalmic. Ask your doctor if contact lenses can be reinserted after application of the medication. Loteprednol and tobramycin ophthalmic may contain a preservative (benzalkonium chloride), which may cause discoloration of contact lenses.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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