Generic Name: mannitol
- What is mannitol?
- What are the possible side effects of mannitol?
- What is the most important information I should know about mannitol?
- What should I discuss with my health care provider before receiving mannitol?
- How is mannitol given?
- What happens if I miss a dose?
- What happens if I overdose?
- What should I avoid while receiving mannitol?
- What other drugs will affect mannitol?
- Where can I get more information?
What is mannitol?
Mannitol is a diuretic.
Mannitol is used to force urine production in people with acute (sudden) kidney failure. Increased urine production helps to keep the kidneys from shutting down, and also speeds up elimination of certain toxic substances in the body.
Mannitol is also used to reduce swelling and pressure inside the eye or around the brain.
Mannitol may also be used for purposes not listed in this medication guide.
What are the possible side effects of mannitol?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers right away if you have:
- swelling in your hands or feet;
- anxiety, sweating, severe shortness of breath, cough with foamy mucus, chest pain;
- painful or difficult urination;
- a light-headed feeling, like you might pass out;
- pain, burning, irritation, or skin changes where the injection was given;
- dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
- signs of an electrolyte imbalance--dry mouth, increased thirst, confusion, fast heart rate, increased urination, muscle pain or weakness, feeling light-headed, fainting, or seizure (convulsions); or
- signs of a kidney problem--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath.
Common side effects may include:
- increased urination;
- nausea, vomiting;
- fever, chills, headache, runny nose;
- swelling, rapid weight gain;
- chest pain;
- skin rash; or
- dizziness, blurred vision.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about mannitol?
You should not receive mannitol if you have severe kidney disease, lung swelling or congestion, severe dehydration, bleeding in your brain not caused by surgery, or if your kidneys have already shut down and you are unable to urinate.
What should I discuss with my health care provider before receiving mannitol?
You should not receive mannitol if you are allergic to it, or if you have:
- severe or long-term kidney disease;
- swelling or congestion in your lungs;
- bleeding in your brain that is not related to surgery;
- severe dehydration; or
- if your kidneys have already shut down and you are unable to urinate.
To make sure mannitol is safe for you, tell your doctor if you have:
- a history of kidney disease;
- heart disease; or
- an electrolyte imbalance (such as low levels of potassium or magnesium in your blood).
It is not known whether mannitol passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How is mannitol given?
Mannitol is injected into a vein through an IV. A healthcare provider will give you this injection.
Mannitol must be given slowly through an IV infusion, and you may receive the medication around the clock.
To be sure mannitol is helping your condition and not causing harmful effects, your blood will need to be tested often. This will help your doctor determine how long to treat you with mannitol. Your heart function will also need to be tested.
What happens if I miss a dose?
Because you will receive mannitol in a clinical setting, you are not likely to miss a dose.
What happens if I overdose?
Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid while receiving mannitol?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What other drugs will affect mannitol?
Other drugs may interact with mannitol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Where can I get more information?
Your doctor or pharmacist can provide more information about mannitol.
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