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minocycline (Dynacin, Minocin, Minocin PAC)

Brand Names: Dynacin, Minocin, Minocin PAC, Minolira, Myrac, Solodyn, Vectrin, Ximino

Generic Name: minocycline

What is minocycline?

Minocycline is a tetracycline antibiotic that is used to treat many different bacterial infections, such as urinary tract infections, respiratory infections, skin infections, severe acne, gonorrhea, tick fever, chlamydia, and others.

Minocycline may also be used for purposes not listed in this medication guide.

What are the possible side effects of minocycline?

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, fever, swollen glands, joint pain, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Call your doctor at once if you have:

  • bronchospasm (wheezing, chest tightness, trouble breathing);
  • a seizure;
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath;
  • low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath;
  • increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, vision problems, pain behind your eyes; or
  • signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, loss of appetite, easy bruising or bleeding, dark urine, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • numbness, tingling, burning pain;
  • hair loss;
  • discoloration of you skin or nails.
  • dizziness, spinning sensation;
  • muscle or joint pain;
  • nausea, diarrhea, loss of appetite;
  • swollen tongue, cough, trouble swallowing;
  • rash, itching; or
  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about minocycline?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What should I discuss with my healthcare provider before taking minocycline?

You should not take this medicine if you are allergic to minocycline or to similar antibiotics such as demeclocycline, doxycycline, or tetracycline.

If you are using minocycline to treat gonorrhea, your doctor may test you to make sure you do not also have syphilis, another sexually transmitted disease.

Tell your doctor if you have ever had:

You should not use minocycline if you are pregnant. It could harm the unborn baby or cause permanent tooth discoloration later in life. Use effective birth control to prevent pregnancy while you are using this medicine, whether you are a man or a woman.

Tell your doctor right away if a pregnancy occurs while either the mother or the father is taking minocycline. The use of this medicine by either parent may cause tooth discoloration later in the baby's life.

Minocycline can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

Minocycline passes into breast milk and may affect bone and tooth development in a nursing baby. You should not breast-feed while you are taking minocycline.

Do not give this medicine to a child without medical advice. Minocycline can cause permanent yellowing or graying of the teeth in children younger than 8 years old.

How should I take minocycline?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take this medicine with a full glass of water.

You may take minocycline with or without food.

Do not crush, chew, or break an extended-release capsule or tablet. Swallow it whole.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Minocycline will not treat a viral infection such as the flu or a common cold.

If you use this medicine long-term, you may need frequent medical tests. You may also need to stop taking minocycline for a short time if you need surgery.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using minocycline.

Store at room temperature away from moisture, heat, and light.

Throw away any minocycline not used before the expiration date on the medicine label.

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What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include dizziness, nausea, or vomiting.

What should I avoid while taking minocycline?

For 2 hours before or after you take minocycline: Avoid taking antacids, laxatives, multivitamins, or supplements that contain calcium, magnesium, or iron. These other medicines can make it harder for your body to absorb minocycline.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Minocycline could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

What other drugs will affect minocycline?

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may affect minocycline, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about minocycline.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Reviewed on 7/23/2019

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