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Medications and Drugs

Brand Names: Levophed Bitartrate

Generic Name: norepinephrine (Pronunciation: nor ep i NEF rin)

What is norepinephrine (Levophed Bitartrate)?

Norepinephrine is similar to adrenaline. It works by constricting (narrowing) the blood vessels and increasing blood pressure and blood glucose (sugar) levels.

Norepinephrine is used to treat life-threatening low blood pressure (hypotension) that can occur with certain medical conditions or surgical procedures. This medication is often used during CPR (cardio-pulmonary resuscitation).

Norepinephrine may also be used for purposes not listed in this medication guide.

What are the possible side effects of norepinephrine (Levophed Bitartrate)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:

  • pain, burning, irritation, discoloration, or skin changes where the injection is given;
  • sudden numbness, weakness, or cold feeling anywhere in your body;
  • slow or uneven heart rate;
  • blue lips or fingernails, mottled skin;
  • urinating less than usual or not at all;
  • trouble breathing;
  • problems with vision, speech, or balance; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about norepinephrine (Levophed Bitartrate)?

If possible before receiving norepinephrine, tell your doctor if you have high blood pressure, diabetes, coronary artery disease, circulation problems, varicose veins, overactive thyroid, asthma, or a sulfite allergy.

Also tell your doctor about all other medicines you use, especially blood pressure medication or an antidepressant.

In an emergency situation it may not be possible before you are treated to tell your caregivers about your health conditions or if you are pregnant or breast feeding. Make sure any doctor caring for you afterward knows that you have received this medication.

Tell your caregivers at once if you have a serious side effect such as cold feeling anywhere in your body, blue lips or fingernails, trouble breathing, urinating less than usual, irritation or skin changes where the medicine is injected, slow heart rate, sudden numbness or weakness, confusion, severe headache, or problems with vision, speech, or balance.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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