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Medications and Drugs

Weight Loss: Top 10 Habits That Can Help You Lose Weight

Brand Names: Qsymia

Generic Name: phentermine and topiramate (Pronunciation: FEN ter meen and toe PIR a mate)

What is phentermine and topiramate (Qsymia)?

Phentermine is an appetite suppressant similar to an amphetamine. Topiramate is a seizure medication, also called an anticonvulsant.

The combination of phentermine and topiramate is used together with diet and exercise to treat obesity. This medication is sometimes used to treat obesity that may be related to diabetes, high cholesterol, or high blood pressure.

Phentermine and topiramate will not treat any underlying condition you have (such as heart disease, diabetes, high blood pressure). Keep taking any other medications your doctor has prescribed to treat these conditions.

Phentermine and topiramate may also be used for purposes not listed in this medication guide.

What are the possible side effects of phentermine and topiramate (Qsymia)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking this medication and call your doctor at once if you have a serious side effect such as:

  • pounding heartbeats or fluttering in your chest;
  • depressed mood, thoughts of suicide or hurting yourself;
  • trouble concentrating, problems with thinking or speech, feeling like you might pass out;
  • blurred vision, eye pain, or seeing halos around lights;
  • low blood sugar (headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery);
  • severe pain in your lower back, red or pink urine;
  • feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, seizure).

Less serious side effects may include:

  • mild dizziness, anxiety, feeling tired or irritable;
  • constipation;
  • memory problems, sleep problems (insomnia);
  • numbness of tingly feeling; or
  • altered sense of taste, dry mouth, or an unpleasant taste in your mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about phentermine and topiramate (Qsymia)?

This medication can harm an unborn baby or cause birth defects. Do not use phentermine and topiramate if you are pregnant.

You should not take this medication if you are allergic to phentermine (Adipex-P, Oby-Cap, Suprenza, T-Diet, Zantryl) or topiramate (Topamax), or if you have glaucoma or overactive thyroid.

Do not use phentermine and topiramate if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Before you take phentermine and topiramate, tell your doctor if you have high blood pressure, heart disease, diabetes, liver or kidney disease, low blood levels of potassium, or if you have had a heart attack or stroke in the past 6 months.

Phentermine may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

Do not stop taking phentermine and topiramate suddenly, or you could have a seizure (convulsions). You may need to use less and less before you stop the medication completely. Ask your doctor how to avoid seizures when you stop using phentermine and topiramate.



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Identifier Tool

Need help identifying pills and medications?
Use the pill finder tool on RxList.

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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Identifier Tool

Need help identifying pills and medications?
Use the pill finder tool on RxList.



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