piroxicam (Feldene)

Brand Names: Feldene

Generic Name: piroxicam

• What is piroxicam (Feldene)?
• What are the possible side effects of piroxicam (Feldene)?
• What is the most important information I should know about piroxicam (Feldene)?
• What should I discuss with my healthcare provider before taking piroxicam (Feldene)?
• How should I take piroxicam (Feldene)?
• What happens if I miss a dose (Feldene)?
• What happens if I overdose (Feldene)?
• What should I avoid while taking piroxicam (Feldene)?
• What other drugs will affect piroxicam (Feldene)?
• Where can I get more information (Feldene)?

Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID).

Piroxicam is used to treat pain or inflammation caused by osteoarthritis or rheumatoid arthritis.

Piroxicam may also be used for purposes not listed in this medication guide.

000693220_PB

capsule, blue/red, imprinted with FELDENE, PFIZER 322

000693230_PB

capsule, red, imprinted with FELDENE, PFIZER323

000930756_PB

capsule, green/light green, imprinted with 93 756, 93 756

000930757_PB

capsule, green, imprinted with 93 757, 93 757

422910674_PB

capsule, green/light green, imprinted with 93 756, 93 756

422910677_PB

capsule, green, imprinted with 93 757, 93 757

597620140_PB

capsule, blue/red, imprinted with FELDENE, PFIZER 322

597620145_PB

capsule, red, imprinted with FELDENE, PFIZER 323

604290299_PB

capsule, orange/white, imprinted with NP 10

604290300_PB

capsule, orange, imprinted with NP 20

Feldene 20 mg

red, imprinted with FELDENE, PFIZER323

Feldene 20 mg

capsule, red, imprinted with FELDENE, PFIZER323

Piroxicam 10 mg-MYL

capsule, green/yellow, imprinted with MYLAN 1010, MYLAN 1010

Piroxicam 10 mg-TEV

capsule, green, imprinted with 93 756, 93 756

Piroxicam 20 mg-MYL

capsule, green, imprinted with MYLAN 2020, MYLAN 2020

Piroxicam 20 mg-TEV

capsule, green, imprinted with 93 757, 93 757

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.

Stop using piroxicam and call your doctor at once if you have:

• severe headache, blurred vision, pounding in your neck or ears;
• heart problems--swelling, rapid weight gain, feeling short of breath;
• liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
• kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath; or
• low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.

Common side effects may include:

• abnormal liver function tests;
• urination problems;
• upset stomach, heartburn, loss of appetite, stomach pain, nausea, vomiting;
• gas, diarrhea, constipation;
• dizziness, headache;
• itching, rash; or
• ringing in your ears.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Piroxicam can increase your risk of fatal heart attack or stroke. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Piroxicam may also cause stomach or intestinal bleeding, which can be fatal.

You should not use piroxicam if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Piroxicam can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Piroxicam may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using piroxicam, especially in older adults.

Tell your doctor if you have ever had:

• heart disease, high blood pressure, or if you smoke;
• a heart attack, stroke, or blood clot;
• a stomach ulcer or stomach bleeding (especially while using an NSAID);
• asthma; or
• liver or kidney disease.

Taking piroxicam during the last 3 months of pregnancy may harm the unborn baby. Tell your doctor if you are pregnant.

Ovulation (release of an egg from your ovary) could be delayed while you are taking piroxicam. This effect is usually not permanent. You should not take piroxicam while you are trying to get pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Piroxicam is not approved for use by anyone younger than 18 years old.

Follow all directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Use the lowest dose that is effective in treating your condition.

It may take up to 2 weeks before your symptoms improve. Keep using the medicine as directed and tell your doctor if your symptoms do not improve.

If you use this medicine long-term, you may need frequent medical tests.

Store at room temperature away from moisture and heat.

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Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, stomach pain, black or bloody stools, or coughing up blood.

Avoid drinking alcohol. It may increase your risk of stomach bleeding.

Avoid taking aspirin while you are taking piroxicam.

Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to piroxicam (such as aspirin, ibuprofen, ketoprofen, or naproxen).

Ask your doctor before using piroxicam if you take an antidepressant. Taking certain antidepressants with an NSAID may cause you to bruise or bleed easily.

Tell your doctor about all your other medicines, especially:

• lithium;
• methotrexate;
• a blood thinner or other medication used to prevent blood clots;
• heart or blood pressure medication, including a diuretic or "water pill"; or
• steroid medicine (such as prednisone).

This list is not complete. Other drugs may affect piroxicam, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Your pharmacist can provide more information about piroxicam.

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