Brand Names: Xifaxan
Generic Name: rifaximin
- What is rifaximin (Xifaxan)?
- What are the possible side effects of rifaximin (Xifaxan)?
- What is the most important information I should know about rifaximin (Xifaxan)?
- What should I discuss with my healthcare provider before taking rifaximin (Xifaxan)?
- How should I take rifaximin (Xifaxan)?
- What happens if I miss a dose (Xifaxan)?
- What happens if I overdose (Xifaxan)?
- What should I avoid while taking rifaximin (Xifaxan)?
- What other drugs will affect rifaximin (Xifaxan)?
- Where can I get more information (Xifaxan)?
What is rifaximin (Xifaxan)?
Rifaximin is used to treat travelers' diarrhea caused by Escherichia coli (E. coli) in adults and children who are at least 12 years old. Most people get this infection by eating food or drinking fluids that have been contaminated with the E. coli bacteria.
Rifaximin is also used to lower the risk of a decline in brain function in adults with liver failure. Brain function can be affected when the liver stops working and cannot remove toxic substances from the body.
Rifaximin may also be used for purposes not listed in this medication guide.
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round, brown, imprinted with XS
What are the possible side effects of rifaximin (Xifaxan)?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);
- fever; or
- fluid build-up around the stomach--rapid weight gain, stomach pain and bloating, trouble breathing while lying down.
Common side effects may include:
- swelling in your hands or feet;
- headache, dizziness;
- tiredness; or
- abnormal liver function tests.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about rifaximin (Xifaxan)?
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What should I discuss with my healthcare provider before taking rifaximin (Xifaxan)?
Tell your doctor if you have ever had:
Rifaximin should not be given to a child younger than 12 years old.
How should I take rifaximin (Xifaxan)?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take rifaximin with or without food.
For travelers' diarrhea, rifaximin is usually taken for only 3 days. For IBS, rifaximin is usually taken for 2 weeks at a time. Follow your doctor's dosing instructions very carefully.
Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Rifaximin will not treat a viral infection such as the flu or a common cold.
Do not share this medicine with another person, even if they have the same symptoms you have.
Call your doctor if your symptoms do not improve after 24 to 48 hours, or if they get worse while using rifaximin.
Rifaximin does not treat all bacterial forms of travelers' diarrhea.
Store at room temperature away from moisture and heat.
What happens if I miss a dose (Xifaxan)?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose (Xifaxan)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking rifaximin (Xifaxan)?
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.
What other drugs will affect rifaximin (Xifaxan)?
Tell your doctor about all your other medicines, especially:
- warfarin (Coumadin, Jantoven);
- an antibiotic--clarithromycin, erythromycin;
- antiviral medicine--ritonavir, saquinavir; or
- heart or blood pressure medicine--amiodarone, quinidine, verapamil.
This list is not complete. Other drugs may affect rifaximin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Where can I get more information (Xifaxan)?
Your pharmacist can provide more information about rifaximin.
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