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Medications and Drugs

Brand Names: Requip, Requip XL

Generic Name: ropinirole (oral) (Pronunciation: roe PIN i role)

What is ropinirole (Requip, Requip XL)?

Ropinirole has some of the same effects as a chemical called dopamine, which occurs naturally in your body. Low levels of dopamine in the brain are associated with Parkinson's disease.

Ropinirole is used to treat symptoms of Parkinson's disease, such as stiffness, tremors, muscle spasms, and poor muscle control. Ropinirole is also used to treat restless legs syndrome (RLS).

Ropinirole may also be used for other purposes not listed in this medication guide.

Requip 0.25 mg

pentagonal, white, imprinted with 4890, SB

Requip 0.5 mg

pentagonal, yellow, imprinted with 4891, SB

Requip 1 mg

pentagonal, green, imprinted with 4892, SB

Requip 2 mg

pentagonal, pink, imprinted with 4893, SB

Requip 3 mg

pentagonal, purple, imprinted with 4895, SB

Requip 4 mg

pentagonal, brown, imprinted with 4896, SB

Requip 5 mg

pentagonal, blue, imprinted with 4894, SB

Ropinirole 0.5 mg-ROX

round, yellow, imprinted with 54 337

Ropinirole 3 mg-ROX

round, brown, imprinted with 54 575

Ropinirole 4 mg-ROX

round, yellow, imprinted with 54 273

Ropinirole 5 mg-ROX

round, blue, imprinted with 54 722

Ropinrole 0.25 mg-MYL

round, white, imprinted with M, N25

Ropinrole 0.25 mg-ROX

round, white, imprinted with 54 511

Ropinrole 0.25 mg-TEV

round, white, imprinted with 9 3, 5282

Ropinrole 0.5 mg-MYL

round, green, imprinted with M, N 5

Ropinrole 0.5 mg-TEV

round, yellow, imprinted with 9 3, 5283

Ropinrole 1 mg-MYL

round, green, imprinted with M, N10

Ropinrole 1 mg-ROX

round, green, imprinted with 54 751

Ropinrole 1 mg-TEV

round, yellow, imprinted with 9 3, 5284

Ropinrole 2 mg-MYL

round, peach, imprinted with M, N 20

Ropinrole 2 mg-ROX

round, peach, imprinted with 54 231

Ropinrole 2 mg-TEV

round, peach, imprinted with 9 3, 5285

Ropinrole 3 mg-MYL

round, lavender, imprinted with M, N30

Ropinrole 3 mg-TEV

round, red, imprinted with 9 3, 5286

Ropinrole 4 mg-MYL

round, white, imprinted with M, N 40

Ropinrole 4 mg-TEV

round, tan, imprinted with 9 3, 5287

Ropinrole 5 mg-TEV

round, blue, imprinted with 9 3, 5288

What are the possible side effects of ropinirole (Requip, Requip XL)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • feeling like you might pass out;
  • fever, stiff muscles, confusion, sweating, fast or uneven heartbeats (especially if you stop taking ropinirole or use a lower dose);
  • hallucinations;
  • tremors (uncontrolled shaking); or
  • tight feeling in your chest, trouble breathing.

Call your doctor promptly if you fall asleep during a daily activity, if you faint, or if you have hallucinations (hearing or seeing something that is not there). Your doctor may want you to stop taking ropinirole, or take a lower dose.

Less serious side effects may occur, such as:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about ropinirole (Requip, Requip XL)?

Ropinirole may cause you to fall asleep during normal daytime activities such as working, talking, eating, or driving. You may fall asleep suddenly, even after feeling alert. Tell your doctor if you have any problems with daytime sleepiness or drowsiness. If you are unsure of how this medicine will affect you, be careful if you drive or do anything that requires you to be awake and alert.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medication. Talk with your doctor if you believe you have any intense or unusual urges while taking ropinirole.

Do not share this medication with another person, even if they have the same symptoms you do.

Avoid drinking alcohol, which can increase some of the side effects of ropinirole.

Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by ropinirole. Tell your doctor if you regularly use any of these other medicines.

Ropinirole may cause hallucinations (the sensation of hearing or seeing something that is not there), most commonly among elderly people. Call your doctor if you experience hallucinations.

Do not stop using ropinirole or change your dose without first talking to your doctor. You may have side effects such as fever, muscle stiffness, and confusion if you stop the medication suddenly or if you change doses.

Some people taking medicines for Parkinson's disease have developed skin cancer (melanoma). However, people with Parkinson's disease may have a higher risk than most people for developing melanoma. Talk to your doctor about your specific risk and what skin symptoms to watch for. You may need to have regular skin exams.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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