testosterone implant (Testopel Pellets)

Brand Names: Testopel Pellets

Generic Name: testosterone implant

What is testosterone (Testopel Pellets)?

Testosterone is a naturally occurring sex hormone produced in a man's testicles.

Testosterone implants are used in men and boys to treat conditions caused by a lack of testosterone.

Testosterone implants are not for use in treating low testosterone due to getting older. Testosterone implants have not been shown to be safe and effective for enhancing athletic performance.

Testosterone may also be used for purposes not listed in this medication guide.

What are the possible side effects of testosterone implants (Testopel Pellets)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Testosterone implants can increase your risk of heart attack, stroke, or death. Get medical help right away if you have:

Call your doctor at once if you have:

  • swelling in your ankles or feet, rapid weight gain;
  • painful or difficult urination;
  • depression, racing thoughts, paranoia, confusion, hallucinations, changes in personality or behavior;
  • jaundice (yellowing of the skin or eyes);
  • a high fever (above 101.5 degrees F), chills, dizziness, nausea, vomiting;
  • skin that feels thick or hard over the area where the implants were placed;
  • pain, itching, swelling, bruising, bleeding, or drainage where the implants were placed; or
  • if the pellets come out of the skin.

Common side effects may include:

  • having more erections or longer-lasting erections than normal;
  • breast swelling and tenderness;
  • increased or decreased interest in sex;
  • numbness, tingling, burning pain;
  • changes in skin color, acne;
  • changes in hair growth, baldness;
  • nausea, vomiting;
  • headache, anxiety, depression; or
  • abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about testosterone implants (Testopel Pellets)?

You should not be treated with this medicine if you have prostate cancer or male breast cancer.

What should I discuss with my healthcare provider before receiving testosterone implants (Testopel Pellets)?

You should not be treated with this medicine if you have:

Being treated with testosterone implants may increase your risk of enlarged prostate or prostatic cancer. Ask your doctor about your individual risk.

Tell your doctor if you have ever had:

Testosterone implants are not for use in women, and should never be used in a pregnant woman. Testosterone can harm an unborn baby.

How are testosterone implants given (Testopel Pellets)?

Testosterone implants are inserted under the skin on the back side of your hip area, usually once every 3 to 6 months. The implants slowly release testosterone and are absorbed in your body over time.

You will receive testosterone implants with a minor surgical procedure in a clinic or doctor's office.

Follow your doctor's instructions about caring for your surgical incision after receiving testosterone implants.

You may need frequent medical tests. Even if you have no symptoms, tests can help your doctor determine if this medicine is effective.

Testosterone can affect bone growth. Young boys treated with testosterone implants may need x-rays every 6 months to check bone development.

Call your doctor if you have any pain, redness, swelling, tenderness, itching, tingling, bruising, or drainage where the implant was inserted, or if the implant comes through the skin or falls out.

If treatment needs to be stopped, the implants may need to be surgically removed early. Do not try to remove the implants yourself. Your doctor will determine whether you need continued treatment with testosterone implants.

Testosterone implants can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine.


Low Testosterone (Low T) Treatments See Slideshow

What happens if I miss a dose (Testopel Pellets)?

Call your doctor for instructions if you miss an appointment for your testosterone implants.

What happens if I overdose (Testopel Pellets)?

Since the testosterone implant contains a specific amount of the medicine, you are not likely to receive an overdose.

What should I avoid while using testosterone implants (Testopel Pellets)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect testosterone implants (Testopel Pellets)?

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may affect testosterone implants, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information (Testopel Pellets)?

Your pharmacist can provide more information about testosterone.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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Reviewed on 3/17/2022

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