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Medications and Drugs

Brand Names: Trifluridine, Viroptic

Generic Name: trifluridine ophthalmic (Pronunciation: trye FLURE i deen off THAL mik)

What is trifluridine ophthalmic (Trifluridine, Viroptic)?

Trifluridine ophthalmic is an antiviral medication. It fights eye infections that are caused by certain viruses.

Trifluridine ophthalmic is used to treat eye infections caused by the herpes simplex virus, which can lead to swelling or ulcers in the eyelids or cornea (surface of the eyeball).

Trifluridine ophthalmic may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of trifluridine ophthalmic (Trifluridine, Viroptic)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using trifluridine ophthalmic and call your doctor at once if you have any of these serious side effects:

  • severe swelling around your eyes;
  • tunnel vision; or
  • severe pain, burning, or other irritation of your eyes.

Keep using the medication and talk to your doctor if you have any of these less serious side effects:

  • mild eye pain, burning, stinging, itching, or redness;
  • blurred vision; or
  • feeling of pressure inside the eye.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about trifluridine ophthalmic (Trifluridine, Viroptic)?

Do not use this medication if you are allergic to trifluridine. This medication will not treat an infection that is caused by bacteria or fungus.

The usual dose of trifluridine ophthalmic is one drop into the affected eye every 2 hours while you are awake. Do not use more than 9 drops in the course of one full day.

Once your condition improves, you may need to keep using the medication 4 times daily (up to 5 drops per day) for another 7 days. Your doctor should check your eyes to determine how long you need to use the medicine.

If you wear contact lenses, remove them before applying trifluridine ophthalmic. Ask your doctor if contact lenses can be reinserted after putting in the eye drops.

Avoid using other eye medications while using trifluridine ophthalmic, unless your doctor has told you to.

Trifluridine ophthalmic may cause blurred vision. Be careful if you drive, operate machinery, or do anything else that requires you to be able to see clearly.

Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use the eye drops if the liquid has changed colors or has particles in it.

Contact your doctor if your symptoms do not improve, or if they get worse after using this medication for 7 days.

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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