Brand Names: Tridione
Generic Name: trimethadione
- What is trimethadione (Tridione)?
- What are the possible side effects of trimethadione (Tridione)?
- What is the most important information I should know about trimethadione (Tridione)?
- What should I discuss with my healthcare provider before taking trimethadione (Tridione)?
- How should I take trimethadione (Tridione)?
- What happens if I miss a dose (Tridione)?
- What happens if I overdose (Tridione)?
- What should I avoid while taking trimethadione (Tridione)?
- What other drugs will affect trimethadione (Tridione)?
- Where can I get more information (Tridione)?
What is trimethadione (Tridione)?
Trimethadione is an anti-epileptic medication, also called an anticonvulsant.
Trimethadione is usually given after other seizure medicines have been tried without success.
Trimethadione may also be used for purposes not listed in this medication guide.
What are the possible side effects of trimethadione (Tridione)?
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have:
- vision problems, droopy eyelids;
- the first sign of any skin rash, no matter how mild;
- unusual muscle weakness, trouble speaking or swallowing;
- swelling in your feet or ankles;
- low blood cell counts--fever, chills, flu-like symptoms, swollen gums, mouth sores, skin sores, rapid heart rate, pale skin, easy bruising, unusual bleeding, feeling light-headed;
- lupus-like syndrome--joint pain or swelling with fever, swollen glands, muscle aches, chest pain, butterfly-shaped skin rash on your cheeks;
- kidney problems--little or no urinating, painful or difficult urination, rapid weight gain;
- liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
- severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
- changes in mood or behavior; or
- increased seizures.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about trimethadione (Tridione)?
You should not stop using trimethadione suddenly. Stopping suddenly may make your condition worse.
What should I discuss with my healthcare provider before taking trimethadione (Tridione)?
You should not use trimethadione if you are allergic to it.
To make sure trimethadione is safe for you, tell your doctor if you have:
- liver disease;
- kidney disease;
- depression, a mood disorder, or history of suicidal thoughts or actions;
- eye problems;
- a blood cell disorder such as anemia or low white blood cells;
- lupus; or
- myasthenia gravis (a nerve-muscle disorder).
You may have thoughts about suicide while taking this medicine. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed. Your family or other caregivers should also be alert to changes in your mood or symptoms.
If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of trimethadione on the baby.
Do not start or stop taking trimethadione during pregnancy without your doctor's advice. Trimethadione may cause harm to an unborn baby, but having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant. You may need to use a different seizure medicine.
If you have taken this medicine during pregnancy, be sure to tell the doctor who delivers your baby about your trimethadione use. Both you and the baby may need to receive medications to prevent excessive bleeding during delivery and just after birth.
It is not known whether trimethadione passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How should I take trimethadione (Tridione)?
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.
The chewable tablet may be chewed or swallowed whole.
While using trimethadione, you may need frequent blood and urine tests. You must remain under the care of a doctor while taking this medicine.
Do not stop using trimethadione suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.
Store in the refrigerator, do not freeze. Keep the bottle tightly closed when not in use.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
What happens if I miss a dose (Tridione)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Tridione)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking trimethadione (Tridione)?
This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Do not drink alcohol while taking this medicine.
What other drugs will affect trimethadione (Tridione)?
Taking this medicine with other drugs that make you sleepy can worsen this effect. Ask your doctor before taking trimethadione with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety or depression.
Other drugs may interact with trimethadione, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Where can I get more information (Tridione)?
Your pharmacist can provide more information about trimethadione.
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