Brand Names: Histex, Histex PD Drops, Histex PDX, Histex Syrup, M-Hist PD, Vanaclear PD, Vanahist PD
Generic Name: triprolidine
- What is triprolidine?
- What are the possible side effects of triprolidine?
- What is the most important information I should know about triprolidine?
- What should I discuss with my healthcare provider before taking triprolidine?
- How should I take triprolidine?
- What happens if I miss a dose?
- What happens if I overdose?
- What should I avoid while taking triprolidine?
- What other drugs will affect triprolidine?
- Where can I get more information?
What is triprolidine?
Triprolidine is an antihistamine that is used to treat sneezing, runny nose, itchy nose and throat, and itchy or watery eyes caused by allergies such as hay fever.
Triprolidine may also be used for purposes not listed in this medication guide.
What are the possible side effects of triprolidine?
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using triprolidine and call your doctor at once if you have:
- painful or difficult urination.
Common side effects may include:
- dizziness, drowsiness;
- blurred vision;
- dry mouth, nose, or throat;
- constipation;
- increased urination; or
- feeling nervous or restless (especially in children).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about triprolidine?
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
You should not use antihistamine medication to make a child sleepy.
What should I discuss with my healthcare provider before taking triprolidine?
You should not use triprolidine if you are allergic to it.
Ask a doctor or pharmacist if this medicine is safe to use if you have:
- a breathing disorder such as chronic bronchitis or emphysema;
- glaucoma; or
- an enlarged prostate and urination problems.
Ask a doctor before using this medicine if you are pregnant or breastfeeding.
This medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).
How should I take triprolidine?
Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use until your symptoms clear up.
Always follow directions on the medicine label about giving cough or cold medicine to a child. Do not use the medicine only to make a child sleepy. Death can occur from the misuse of cough or cold medicines in very young children.
You must chew the chewable tablet before you swallow it.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.
If you need surgery or medical tests, tell the doctor ahead of time if you have taken this medicine within the past few days.
Store at room temperature away from moisture and heat. Do not allow liquid medicine to freeze.

QUESTION
Allergies can best be described as: See AnswerWhat happens if I miss a dose?
Since triprolidine is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking triprolidine?
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.
Drinking alcohol can increase certain side effects of triprolidine.
Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Triprolidine can decrease sweating and you may be more prone to heat stroke.
What other drugs will affect triprolidine?
Avoid using this medicine with other drugs that cause drowsiness or slow your breathing (such as opioid medicine, a muscle relaxer, or medicine for anxiety or seizures). Ask a doctor or pharmacist before using any other medication, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed in this medication guide.
Where can I get more information?
Your pharmacist can provide more information about triprolidine.
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