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Symptoms and Signs of What Are the Symptoms of Epstein-Barr Virus?

Doctor's Notes on 15 Epstein-Barr Virus (EPV, Mono) Symptoms, Causes, Transmission, Treatments, and Prognosis

Epstein-Barr virus (EBV) is a common herpesvirus that is the cause of infectious mononucleosis (“mono”). EBV infection is passed from person to person mainly by saliva or contact with items and substances contaminated with bodily fluids like saliva (toys, utensils, cups). Children, teens, and young adults are most commonly infected. EBV infection is found throughout the world.

Signs and symptoms of infectious mononucleosis include fever, tiredness, sore throat, headache, and muscle aches. Other associated symptoms can include enlargement of the liver, enlargement of the spleen, rash, enlarged tonsils, and swelling of the lymph nodes. Symptoms typically last for two to four weeks or even longer in some people. There is no vaccine available to prevent EBV infection.

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Medically Reviewed on 3/20/2019


Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.