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Fifth Disease (cont.)

What Are Fifth Disease Symptoms and Signs?

  • Fifth disease usually starts as a mild vague illness and nonspecific symptoms. Low-grade fever occurs 15%-30% of the time, along with nasal congestion and drainage, mild sore throat, fatigue, muscle aches, and a headache. This lasts for several days.
  • Then, seven to 10 days later, the characteristic facial rash (slapped cheeks appearance) develops abruptly. Typically, the facial rash is bright red. The child looks as if a hand has been slapped across his or her face. This rash fades within approximately four days.
  • As the slapped cheek skin changes fade, a light pink rash begins on the arms, then may spread to the trunk, buttocks, and thighs. This gradually fades to a lacy pattern lasting three to four days and then clears.
Medically Reviewed by a Doctor on 11/10/2016

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Read What Your Physician is Reading on Medscape

Pediatrics, Fifth Disease or Erythema Infectiosum »

Erythema infectiosum is usually a benign childhood condition characterized by a classic slapped-cheek and lacy exanthem.

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