©2018 WebMD, Inc. All rights reserved. eMedicineHealth does not provide medical advice, diagnosis or treatment. See Additional Information.


What other names is Guayule known by?

Caoutchouc Mexicain, Mexican Rubber, Parthenium argentatum.

What is Guayule?

Guayule is a shrub. The latex is used as a rubber alternative.

Insufficient Evidence to Rate Effectiveness for...

  • Hypoallergenic rubber alternative.
  • Other conditions.
More evidence is needed to rate the effectiveness of guayule for these uses.

How does Guayule work?

There isn't enough information to know how guayule might work as a medicine.

Are there safety concerns?

It isn't known if guayule is safe or what the possible side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of guayule during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Dosing considerations for Guayule.

The appropriate dose of guayule depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for guayule. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

Health Solutions From Our Sponsors

Reviewed on 9/17/2019

Cornish K, Lytle CD. Viral impermeability of hypoallergenic, low protein, guayule latex films. J Biomed Mater Res 1999;47(3):434-7. View abstract.

Foster MA, Coffelt TA. Guayule agronomics: establishment, irrigated production, and weed control. Industrial Crops Prod 2005;22:27-40.

Nakayama FS. Guayule future development. Industrial Crops Prod 2005;22:3-13.

Pan Z, Durst F, Werck-Reichhart D, et al. The major protein of guayule rubber particles is a cytochrome P450. Characterization based on cDNA cloning and spectroscopic analysis of the solubilized enzyme and its reaction products. J Biol Chem 1995;270(15):8487-94. View abstract.

Parra-Delgado H, Garcia-Pillado F, Sordo M, et al. Evaluation of the cytotoxicity, cytostaticity and genotoxicity of argentatins A and B from Parthenium argentatum (Gray). Life Sci 2005;77(22):2855-65. View abstract.

Siler DJ, Cornish K, Hamilton RG. Absence of cross-reactivity of IgE antibodies from subjects allergic to Hevea brasiliensis latex with a new source of natural rubber latex from guayule (Parthenium argentatum). J Allergy Clin Immunol 1996;98(5 Pt 1):895-902. View abstract.

Health Solutions From Our Sponsors