Hardening of the Arteries (cont.)
IN THIS ARTICLE
National Heart, Lung, and Blood Institute (NHLBI), Information for Patients and the Public, Heart and Vascular Diseases
National Heart, Lung, and Blood Institute (NHLBI), National Cholesterol Education Program
Medically reviewed by Robert J. Bryg, MD; Board Certified Internal Medicine with subspecialty in Cardiovascular Disease
Last Editorial Review: 8/12/2015
Shabir Bhimji, MD
Shehnaz Shaikh, MD
Alan D Forker, MD
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Atherosclerosis is a disease of large and medium-sized muscular arteries and is characterized by endothelial dysfunction, vascular inflammation, and the buildup of lipids, cholesterol, calcium, and cellular debris within the intima of the vessel wall.