Hepatitis B (HBV, Hep B) Topic Guide

Vaccinations are some of the most important tools available for preventing disease. Most children get all their shots during childhood. Parents should consult their doctors about which vaccines their children should have and when. Keep track of your children's immunizations yourself.

Hepatitis B is an infection of the liver caused by the hepatitis B virus (HBV). Hepatitis can be potentially prevented by the available hepatitis vaccines for both infants, children, and adults. Hepatitis B treatment options include a class of medications called nucleoside/nucleotide analogues, and interferons. Side effects, drug interactions, warnings and precautions should be discussed with a doctor prior to starting treatment with hepatitis B medicaitons.

At least 45,000 adults in the United States die of complications of influenza, pneumococcal infections, and hepatitis B each year. Adults need the following vaccines: chickenpox, hepatitis B, MMR, Td/Tdap, flu, shingles, and pneumococcal.

Most immunizations are not required under International Health Requirements but are recommended. Anyone lacking certain region- or country-specific immunizations may be denied entry into or exit from a country.

Liver biopsy involves the removal of a small piece of tissue from the liver. Reasons for liver biopsy is to diagnose disease, monitor disease, and monitor the effectiveness of therapy. Risk of liver biopsy include hematoma, bleeding, striking another organ, and tumor tracking. Types of liver biopsy include percutaneous, transjugular, and intraoperative liver biopsy.

Liver blood tests are used to check the levels and function of liver enzymes in the blood called AST and ALT or aminotransferases in the blood. Symptoms of elevated or high liver enzymes in the blood include fever, abdominal pain, poor appetite, itching, and nausea. Normal levels of liver enzymes in blood are caused by liver diseases caused by drugs, for example, acetaminophen (Tylenol), pain medications, and statins. Less common causes of abnormal levels of ALT or AST levels in the blood are alcoholic and non-alcoholic liver diseases (NASH), hepatitis, and alcoholism. Normal levels of ALT ranges from about 7-56 units/liter, and 10-40 units/liters for AST. Elevated (high) and low liver enzymes elevated levels of AST and ALT may signify the level of liver damage the person has. A blood sample is sent to the laboratory for measurement. Usually, you doctor will have the results interpreted within a few hours to days. Liver blood tests are used to check normal, elevated (high), and low blood levels of liver enzymes (AST and ALT or aminotransferases). Symptoms of elevated levels of liver enzymes are fever, abdominal pain, poor appetite, and nausea. Drugs, for example, acetaminophen (Tylenol), pain drugs, and statins caused high levels of liver enzymes. Less common causes are NASH, hepatitis, and alcoholism.