How Long Can Babies Live with Holoprosencephaly? Topic Guide

How Long Can Babies Live with Holoprosencephaly? How Long Can Babies Live with Holoprosencephaly?: The life expectancy for holoprosencephaly (HPE) depends on the type. Mild HPE may have no effect on life expectancy, while moderate to severe HPE (lobar HPE, semilobar HPE) life expectancy is beyond one year. Half of children with severe HPE (alobar HPE) die between four to five months of age, and only 20% survive beyond the first year of life.

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