Doctor's Notes on Hypopituitary
Hypopituitarism (hypopituitary) is a condition in which the pituitary gland (a small gland at the base of the brain) does not produce one or more of its hormones or not enough of them to function normally. Hormones produced by the pituitary include prolactin, adrenocorticotropic hormone (ACTH), growth hormone (GH), thyroid-stimulating hormone (TSH), luteinizing hormone (LH) and follicle-stimulating hormone (FSH); each hormone has its particular effects.
- Prolactin – little or no milk production, fatigue, loss of underarm and pubic hair
- ACTH – fatigue, low blood pressure, weight loss, depression, nausea, vomiting
- GH – short stature, low energy, weight gain, decreased exercise tolerance, anxiety, depression
- TSH – constipation, sensitive to cold, weight gain, muscle soreness
- LH and FSH – in women, irregular or no periods, infertility; in men, weakness, loss of body and facial hair, erectile dysfunction, infertility
In addition, the condition may reduce ADH levels resulting in increased thirst and urination.
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.