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Symptoms and Signs of Hypopituitary

Doctor's Notes on Hypopituitary

Hypopituitarism (hypopituitary) is a condition in which the pituitary gland (a small gland at the base of the brain) does not produce one or more of its hormones or not enough of them to function normally. Hormones produced by the pituitary include prolactin, adrenocorticotropic hormone (ACTH), growth hormone (GH), thyroid-stimulating hormone (TSH), luteinizing hormone (LH) and follicle-stimulating hormone (FSH); each hormone has its particular effects.

In addition, the condition may reduce ADH levels resulting in increased thirst and urination.

Causes of hypopituitarism have been linked to tumors, radiation exposures, surgery, meningitis and other diseases; in many individuals with the condition, the causes are not known.

Medical Author:
Medically Reviewed on 3/11/2019


Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.