Picture of Amiodarone
Amiodarone can trigger drug-induced pigmentation of the skin. In this picture, the face of a man is slate gray after taking amiodarone. The bluish skin color (ceruloderma) happens when melanin and lipofuscin accumulate in macrophages and endothelial cells of the dermis. This type of skin discoloration is reversible. Most cases will take about one year to resolve completely. In this patient, it took 33 months for the bluish skin color to completely disappear.
Text Reference: Circulation, vol. 67, 1983: “Side Effects of Long-term Amiodarone Therapy”