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Vascular, Lymphatic and Systemic Conditions

Picture of Hereditary Hemorrhagic Telangiectasia

Picture of Hereditary Hemorrhagic Telangiectasia

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disease that involves the occurrence of arteriovenous malformations (AVMs). These abnormal blood vessels connect arteries directly to veins. A network of capillaries normally separates arteries and veins. AVMs are groups of blood vessels that do not have these capillaries. Blood flow through AVMs causes increased pressure, which leads to ruptures and bleeding. Recurrent nosebleeds are common with the disorder. Bleeding in the brain, lungs, liver, and other organs may also occur.

Image Source: Color Atlas & Synopsis of Pediatric Dermatology Kay Shou-Mei Kane, Jen Bissonette Ryder, Richard Allen Johnson, Howard P. Baden, Alexander Stratigos Copyright 2002 by The McGraw-Hill Companies. All rights reserved.

Text Reference: Genetics Home Reference: "Hereditary Hemorrhagic Telangiectasia"