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What other names is Inosine known by?

Hypoxanthine Riboside, Hypoxanthosine, Inosina, 2,3-Diphosphoglycerate, 6-9 Dihydro-9-B-D-ribofuranosyl-1H-puin-6-one, 9-B-D-ribofuranosylhypoxanthine.

What is Inosine?

Inosine is a chemical that can be made in a laboratory. It is used as medicine.

People take inosine for improving their athletic performance.

Likely Ineffective for...

  • Improving athletic performance.

Insufficient Evidence to Rate Effectiveness for...

How does Inosine work?

There is information that suggests inosine might help nerve branches (axons) grow from healthy nerves to injured nerve cells in the brain and spinal cord. If this is true, inosine might be useful in treating spinal cord injuries, but more research in people is needed to be sure.

Are there safety concerns?

It is not known if inosine is safe or what the possible side effects might be.

Special Precautions & Warnings:

Pregnancy and breast-feeding: Not enough is known about the use of inosine during pregnancy and breast-feeding. Stay on the safe side and avoid use.

Gout: Taking inosine might make gout worse.

Dosing considerations for Inosine.

The appropriate dose of inosine depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for inosine. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).

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Reviewed on 9/17/2019

Benowitz LI, Goldberg DE, Madsen JR, et al. Inosine stimulates extensive axon collateral growth in the rat corticospinal tract after injury. Proc Natl Acad Sci USA 1999;96:13486-90. View abstract.

Starling RD, Trappe TA, Short KR, et al. Effect of inosine supplementation on aerobic and anaerobic cycling performance. Med Sci Sports Exerc 1996;28:1193-8. View abstract.

Williams MH, Kreider RB, Hunter DW, et al. Effect of inosine supplementation on 3-mile treadmill run performance and VO2 peak. Med Sci Sports Exerc 1990;22:517-22. View abstract.


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