Calabacita, Calabaza Hiedra, Coccinia cordifolia, Coccinia grandis, Coccinia indica, Coccinia Índica, Courge Écarlate, Kovai, Little Gourd, Tela Kucha, Tindola.
Ivy gourd is a plant. The leaves, root, and fruit are used to make medicine.
Some people apply ivy gourd leaves directly to the skin for wounds.
Ivy gourd fruit and leaves are used as a vegetable in India and other Asian countries.
How does it work?
Ivy gourd contains chemicals that may reduce blood sugar levels.
Possibly Effective for...
Insufficient Evidence to Rate Effectiveness for...
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Diabetes: Ivy gourd might lower blood sugar. If you have diabetes and use ivy gourd, check your blood sugar carefully.
Surgery: Ivy gourd might lower blood sugar. There is some concern it might interfere with blood sugar control during and after surgery. Stop using ivy gourd at least 2 weeks before a scheduled surgery.
Medications for diabetes (Antidiabetes drugs)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Ivy gourd might lower blood sugar levels. Diabetes medications are also used to lower blood sugar. Taking ivy gourd along with diabetes medications might cause your blood sugar to be too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (Diabeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
The appropriate dose of ivy gourd depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for ivy gourd. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Health Solutions From Our Sponsors
Azad Khan, A. K., AKhtar, S., and Mahtab, H. Coccinia indica in the treatment of patients with diabetes mellitus. Bangladesh Med Res Counc Bull 1979;5(2):60-66. View abstract.
Cefalu, W. T., Ye, J., and Wang, Z. Q. Efficacy of dietary supplementation with botanicals on carbohydrate metabolism in humans. Endocr.Metab Immune.Disord Drug Targets. 2008;8(2):78-81. View abstract.
Chandrasekar, B., Mukherjee, B., and Mukherjee, S. K. Blood sugar lowering potentiality of selected Cucurbitaceae plants of Indian origin. Indian J Med Res 1989;90:300-305. View abstract.
Charoenkiatkul, S., Kriengsinyos, W., Tuntipopipat, S., Suthutvoravut, U., and Weaver, C. M. Calcium absorption from commonly consumed vegetables in healthy Thai women. J Food Sci 2008;73(9):H218-H221. View abstract.
GUPTA, S. S. and VARIYAR, M. C. EXPERIMENTAL STUDIES ON PITUITARY DIABETES. IV. EFFECT OF GYMNEMA SYLVESTRE AND COCCINIA INDICA AGAINST THE HYPERGLYCAEMIC RESPONSE OF SOMATOTROPIN AND CORTICOTROPIN HORMONES. Indian J Med Res 1964;52:200-207. View abstract.
Hardy, M, Coulter, I, Venturupalli, S, Roth, EA, Favreau, J, Morton, SC, and Shekelle, P. Ayurvedic interventions for diabetes mellitus: a systematic review. In: The Cochrane Library 2007;(4)
Hossain, M. Z., Shibib, B. A., and Rahman, R. Hypoglycemic effects of Coccinia indica: inhibition of key gluconeogenic enzyme, glucose-6-phosphatase. Indian J Exp Biol 1992;30(5):418-420. View abstract.
Kamble, S. M., Kamlakar, P. L., Vaidya, S., and Bambole, V. D. Influence of Coccinia indica on certain enzymes in glycolytic and lipolytic pathway in human diabetes. Indian J Med Sci 1998;52(4):143-146. View abstract.
Khan, A. K., AKhtar, S., and Mahtab, H. Treatment of diabetes mellitus with Coccinia indica. Br Med J 4-12-1980;280(6220):1044. View abstract.
Kumar, GP. A Comparative study on the hypolipidemic activity of eleven different pectins. Journal of Food Science and Technology 1997;34(2):103-107.
Kuriyan, R., Rajendran, R., Bantwal, G., and Kurpad, A. V. Effect of supplementation of Coccinia cordifolia extract on newly detected diabetic patients. Diabetes Care 2008;31(2):216-220. View abstract.
Mallick C, Chatterjee K, Mandal U, and Ghosh D. Protective effects of MTEC, a formulated herbal drug on glycemic indices and testicular dysfunctions in streptozotocin-induced diabetic rat. J HERBS SPICES MEDICINAL PLANT 2007;13(4):69-91.
Mallick, C., De, D., and Ghosh, D. Correction of protein metabolic disorders by composite extract of Musa paradisiaca and Coccinia indica in streptozotocin-induced diabetic albino rat: an approach through the pancreas. Pancreas 2009;38(3):322-329. View abstract.
Mallick, C., Mandal, S., Barik, B., Bhattacharya, A., and Ghosh, D. Protection of testicular dysfunctions by MTEC, a formulated herbal drug, in streptozotocin induced diabetic rat. Biol Pharm Bull 2007;30(1):84-90. View abstract.
Pari, L. and Venkateswaran, S. Protective effect of Coccinia indica on changes in the fatty acid composition in streptozotocin induced diabetic rats. Pharmazie 2003;58(6):409-412. View abstract.
Prasuna, C. P., Chakradhar, R. P., Rao, J. L., and Gopal, N. O. EPR as an analytical tool in assessing the mineral nutrients and irradiated food products-vegetables. Spectrochim.Acta A Mol Biomol.Spectrosc. 12-1-2008;71(3):809-813. View abstract.
Sanadi, A. R. and Surolia, A. Studies on a chitooligosaccharide-specific lectin from Coccinia indica. Thermodynamics and kinetics of umbelliferyl glycoside binding. J Biol Chem 2-18-1994;269(7):5072-5077. View abstract.
Sekhar, NR. Studies on the suitability of retortable pouches for packing banana puree and ivy gourd. Indian Food Packer 1991;45(5):29-36.
Singh, N., Singh, S. P., Vrat, S., Misra, N., Dixit, K. S., and Kohli, R. P. A study on the anti-diabetic activity of Coccinia indica in dogs. Indian J Med Sci 1985;39(2):27-9, 42. View abstract.
Venkateswaran, S. and Pari, L. Effect of Coccinia indica leaf extract on plasma antioxidants in streptozotocin- induced experimental diabetes in rats. Phytother.Res 2003;17(6):605-608. View abstract.
Venkateswaran, S. and Pari, L. Effect of Coccinia indica on Blood Glucose, Insulin and KeyHepatic Enzymes in Experimental Diabetes. Pharmaceutical Biology 2002;40(3):165-170.
Venkateswaran, S., Pari, L., Suguna, L., and Chandrakasan, G. Modulatory effect of Coccinia indica on aortic collagen in streptozotocin-induced diabetic rats. Clin Exp Pharmacol Physiol 2003;30(3):157-163. View abstract.
Wasantwisut, E. and Viriyapanich, T. Ivy gourd (Coccinia grandis Voigt, Coccinia cordifolia, Coccinia indica) in human nutrition and traditional applications. World Rev Nutr Diet 2003;91:60-66. View abstract.
Dhanabal SP, Koate CK, Ramanathan M, et al. The hypoglycemic activity of Coccinia indica Wight & Arn. and its influence on certain biochemical parameters. Indian J Pharmacol 2004;36:249-250.
Eshrat MH. Effect of Coccinia indica (L.) and Abroma augsta (L.) on glycemia, lipid profile and on indicators of end-organ damage in streptozotocin induced diabetic rats. Indian J Clin Biochem 2003;18:54-63.
Kar A, Choudhary BK, Bandyopadhyay NG. Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats. J Ethnopharmacol 2003;84:105-8. View abstract.
Khan AK, AKhtar S, Mahtab H. Treatment of diabetes mellitus with Coccinia indica. Br Med J 1980;280:1044.
Kumar GP, Sudheesh S, Vijayalakshmi NR. Hypoglycaemic effect of Coccinia indica: mechanism of action. Planta Med 1993;59:330-2. View abstract.
Munasinghe MAAK, Abeysena C, Yaddehige IS, et al. Blood sugar lowering effect of Coccinia grandis (L.) J. Voight: path for a new drug for diabetes mellitus. Exp Diabetes Res 2011; doi: 10.1155/2011/978762. View abstract.
Shibib BA, Khan LA, Rahman R. Hypoglycaemic activity of Coccinia indica and Momordica charantia in diabetic rats: depression of the hepatic gluconeogenic enzymes glucose-6-phosphatase and fructose-1,6-bisphosphatase and elevation of both liver and red-cell shunt enzyme glucose-6-phosphate dehydrogenase. Biochem J 1993;292:267-70. View abstract.
Venkateswaran S, Pari L. Effect of Coccinia indica leaves on antioxidant status in streptozotocin-induced diabetic rats. J Ethnopharmacol 2003;84:163-8. View abstract.
Yeh GY, Eisenberg DM, Kaptchuk TJ, Phillips RS. Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabetes Care 2003;26:1277-94. View abstract.